Introduction to the production process of eye drops bottle

 Plastic bottles play an important role in people's production and life. No matter what the bottle is, it must be formed and processed, and our common eye drop bottles are no exception. The eye drop bottle is composed of a bottle body, a bottle cap and a dripper. What kind of production technology is used to process the bottle with this structure?

eye drop bottles

Eye drop bottles are generally made of soft low-density polyethylene raw materials through injection-blowing technology. The capacity ranges from 5ml-15ml. First, the injection machine injects the molten plastic into the injection mold to form a tube blank. The microporous hollow punch is formed; then it is moved to the blow mold while it is hot; then the mold is closed and compressed air is introduced from the pipe of the mandrel to inflate the parison and stick to the cavity wall of the mold; After holding pressure, cooling and shaping, the compressed air is released and the mold is opened to take out the plastic part. This process has the following characteristics:

1. The product has exquisite appearance, accurate size, uniform wall thickness and no flash, and the production of parts does not require secondary processing;

2. Plastic products are made by one-time blow molding of injection moulds, with no waste at the mouth and bottom of the bottle, and the mouth is flat and has good sealing performance;

3. The injection parison has a bottom, so there is no split seam at the bottom of the plastic part, which has high strength and high productivity. It is mostly used for mass production of small plastic parts.

The eye drop bottle produced by the injection-blowing process has good sealing properties and a more high-end appearance. This process is also used in the processing of small refined containers and wide-mouth containers such as cosmetics, daily necessities, food and pharmaceutical packaging bottles.

Material is very important when choosing eye drop bottles

 As an important part of drug circulation, pharmaceutical packaging plays an important role in protecting drug safety. For eye drops with high-risk routes of administration, the importance of packaging is particularly important. How to choose a high-quality eye drop bottle, first of all, we must start with the material.

eye drop bottle

With the popularization of electronic products, the resulting market share of ophthalmic drugs has continued to increase, and with the improvement of people's health awareness, attention to drug packaging has also increased. The material of pharmaceutical packaging is the primary consideration when choosing eye drop bottles. The eye drop bottle is used to squeeze the bottle body to achieve eye administration. If the material is too hard, it will not be able to squeeze out, or the amount of medicine will exceed the standard due to excessive force, resulting in waste.

Secondly, as a medicine packaging material, the raw materials of the eye drop bottle must be non-toxic, tasteless, and resistant to most acids and alkalis to ensure that the medicine and the container will not react. Of course, this needs to be proved through actual tests.

In summary, the material of the eye drop bottle is related to whether the eye drops are used smoothly and conveniently, and also related to the safety of drug storage. At present, the eye drop bottles on the market mostly use low-density polyethylene (LDPE) raw materials. Compared with high-density polyethylene, this raw material has good flexibility, resistance to corrosion by most acid and alkali solvents, and will not be squeezed. It produces creases and is a good packaging material.

The importance of eye drop bottle tightness test

 Eye drops are one of the commonly used pharmaceutical dosage forms for eye diseases. For many eye diseases, eye drops have a direct and rapid therapeutic effect. Because it acts directly on the eyes, eye drops have very strict requirements on the transparency, air tightness, and pressure resistance of the pharmaceutical packaging. Among them, the tightness test is an important test index for the eye drop bottle.

5ml eye dropper bottle

Tightness refers to the feature of packaging to prevent other substances from entering or the contents from escaping. In the production process of the eye drop bottle, due to the many production links, leaks, press-throughs, or cracks and pores in the material itself may occur, resulting in small holes or weak points of strength between the inside and the outside. If the sealing performance is not up to standard, external water vapor will enter the package and contact the medicine, and the medicine may be contaminated, invalid or deteriorated, which will endanger the health of the patient. Therefore, to ensure the efficacy of the drug within the validity period, a package with good sealing properties must be provided, and the sealing performance test has become one of the basic test items for many drug packages.

Eye drop bottles are generally made of plastic material that is easy to squeeze, and the common one is low-density polyethylene (LDPE). In the YBB20072012 "Low Density Polyethylene Medical Eye Drop Bottles" standard, specific requirements are made for the sealing test method:

(1) Take several test bottles. Under the condition of a torque of 55-80N·cm, both the mouth and the cap should match properly, and the teeth should not be slippery.

(2) Take several test bottles, open the bottles first, and then tighten the caps (the test bottles use a force measuring wrench to tighten the bottles and caps, the torque is 55-80N·cm), and place them in a container with a suction device Afterwards, add a baffle, immerse in water, vacuum to a vacuum of 20kPa, and maintain for 2 minutes. There should be no water or bubbling in the bottle.

There may be slight differences in national standards for the test methods for the tightness of eye drop bottles, but the purpose is to ensure the safety of the drugs and bring better treatment effects for patients. For the tightness test, the manufacturer of the drug packaging Pharmaceutical companies should pay enough attention.

Eye drop bottle purchase attention

 Eye drops are commonly used drugs in ophthalmology. A bottle of high-quality eye drops requires a high-quality eye drop bottle to protect it. Pharmaceutical companies can consider the following aspects when purchasing eye drop bottles.

eye dropper bottle

1. No matter what raw material you choose, the eye drop bottle must first meet the requirements of non-toxicity and no peculiar smell. The low-density polyethylene (LDPE), polyester (PET) and other materials we see daily can be used as eye drop bottles Based on the raw materials of the drug, the appropriate materials can be selected according to the properties of the drug to better meet its demand for packaging.

2. The airtightness and water vapor permeability of the bottle body and cap. Tightness and water vapor permeability are two important technical indicators of plastic bottles. They have a vital impact on the stability of the packaged product. Pharmaceutical companies need to pay attention to these two indicators when purchasing eye drop bottles.

3. Product quality standards for eye drops. The product quality can be analyzed and judged from the manufacturer's product quality standards, which is convenient for pharmaceutical companies to make correct judgments.

4. Quality assurance system. Auditing suppliers has become an essential part of purchasing eye drop bottles. Through the audit, a comprehensive and correct assessment of the manufacturer's software and hardware facilities, technical equipment, and comprehensive quality level can be made. High-quality manufacturers are more secure in terms of product quality, delivery cycle, and later service.

Eye drops are essential medicines to protect eye health. Pay attention to the importance of eye drops bottles. Choosing high-quality pharmaceutical packaging is a necessary condition to ensure eye health.