Why eye drops bottle can only be used for four weeks after opening

 Eye drops occupies an important position in ophthalmic drugs and are a very common type of drug. Any medicine has a validity period. The validity period of eye drops is generally 1-3 years. If the eye drops bottle is opened, the validity period of the medicine is only four weeks.

eye dropper bottle

The 1-3 year validity period marked on the eye drop bottle packaging refers to the time when the package is unopened. The "People's Republic of China Pharmacopoeia" stipulates that "ophthalmic preparations can be used for up to 4 weeks after being used", even if the drug is still within the validity period. Inside, the eye drops can only be used for up to 4 weeks after opening.

This is because once the eye drops are opened, they are easy to come into contact with microorganisms and tears during storage and use, leading to drug contamination. Under normal circumstances, each eye drop will be available after opening in the manual [Precautions] Maximum time used. Some drugs can be used for less than 4 weeks after opening, and the specific instructions shall prevail. Patients are advised to indicate the opening time on the package after opening the eye drops to avoid expiration and deterioration.

Of course, there are some special cases. If it is a small package of eye drops without preservatives, it will not have any resistance to bacteria and viruses floating in the air after opening. Each small bottle is only used for one time. Open the eye drops bottle After that, it can only be used once, and it needs to be discarded after the medication is finished

Features of eye drops bottle

 With the development of technology and the transformation of people's working methods, eye diseases are more common, and the demand for ophthalmic drugs is also rising, which will drive the market growth of eye drop bottles. what are the characteristics of the eye drop bottles？

5ml eye dropper bottle

The eye drop bottle is the main packaging of ophthalmic drugs. It is composed of a cap, a nozzle and a bottle body. It is generally processed from low-density polyethylene raw materials. It has good flexibility, extensibility, easy processing, and corrosion resistance. Wait. It is a kind of packaging container with convenient use and good sealing performance.

What is an eye drop bottle

 With the development of technology, electronic products such as computers, mobile phones, and tablets have gradually become necessities of people's lives, and eye health problems caused by excessive eye use have become more prominent. Among all eye treatment drugs, eye drops are commonly used, and they are placed in special eye drops bottles.

5ml eye drop bottle

The eye drop bottle is a special pharmaceutical packaging container, mainly used for the packaging of eye drop drugs. This kind of packaging consists of a bottle cap, a nozzle, and a bottle body. The bottle body is made of low-density polyethylene raw materials through injection and blowing technology. The low-density polyethylene has good flexibility, extensibility, electrical insulation, transparency, and easy Processability and certain air permeability. It has good chemical stability, alkali resistance and general organic solvent resistance.

When administering the eye drop bottle, take the supine or sitting position, pull the lower eyelid with the thumb and index finger of the left hand, turn the eyeball upward, hold the bottle with the other hand, and squeeze it with the mouth of the bottle facing downwards Pinch 1 drop of the eye drops, then immediately pull the eyelids, and gently close the eyes, so that the eye drops spread to the entire conjunctival sac.

It should be noted during administration that the eye drop bottle should be kept at a safe distance of more than two centimeters from the eyelid. If the liquid is a suspension, it should be shaken well before use. Under normal circumstances, eye drops should be stored in a cool, dry, and ventilated place, avoid direct sunlight, the mouth of the bottle should be up, and the cap should be tightened to prevent the liquid from leaking.

What is the eye drops container made of

 The eye drops container is composed of a cap, a dropper, and a bottle body, and is a common pharmaceutical packaging for ophthalmic drugs. The material of the packaging plays an important role in maintaining the efficacy of the medicine and protecting the safety during the transportation of the medicine. So, what material is the eye drop bottle made of?

eye drop bottles

Eye drops container is a kind of plastic bottle. Its raw material is mainly low-density polyethylene (LDPE). It is the lightest variety in polyethylene resin. It is milky white, tasteless, odorless, non-toxic, and has no surface. Glossy waxy particles. It has good flexibility, extensibility, electrical insulation, transparency, easy processing and certain air permeability. It has good chemical stability, alkali resistance and general organic solvent resistance. LDPE has been industrialized for more than 70 years. Although with the discovery and development of olefin polymerization catalysts, the variety and output of polyethylene have made great progress, LDPE still occupies an important position, and some pharmaceutical packaging, daily necessities packaging, etc. are used Here comes this raw material.

After adding organic solvent, LDPE is processed by injection blowing process. First, the injection machine injects the molten plastic into the injection mold to form a tube blank. The tube blank is formed on a hollow convex mold with micro holes on the peripheral wall; then it is moved to the blow mold while it is hot; then the mold is closed and passed through the pipe of the mandrel Enter the compressed air to inflate the parison and stick it to the cavity wall of the mold; finally, after holding the pressure, cooling and setting, the compressed air is released and the mold is opened to take out the plastic part.

The eye drops container made of LDPE material is soft, easy to squeeze, and can quickly return to its original shape after squeezing, without creases. Whether it is in terms of the characteristics of the material and the convenience of the patient It is a better raw material for production.

What kind of material is the eye drop bottle

 Eye drops are one of the commonly used drug formulations for ophthalmological diseases, which have direct and quick treatment effects on many ocular diseases. The eye drop bottle is a special packaging for eye drops. The drug needs to be squeezed out of the bottle during administration. There are various materials used for plastic pharmaceutical packaging. Which material is easier to squeeze out the drug?

5ml eye drop bottle

Common raw materials for plastic bottles include polyethylene (PE), polypropylene (PP), polyester (PET), high barrier (EVOH), etc., among which low-density polyethylene (LDPE) and polypropylene can be used as eye drop bottles Both of the raw materials for production are non-toxic and tasteless, and can withstand the corrosion of various acids, alkalis and other solvents. The difference is that low-density polyethylene feels soft and easy to squeeze. Compared with LDPE, polypropylene is harder, less flexible, and fragile at low temperatures. It is generally used in powder bottles or small-capacity liquid bottles.

In terms of ease of use, LDPE material is more in line with the use requirements of eye drop bottles, and will be squeezed without creases, and will return to its original shape. The eye drops are usually administered by the patient themselves. If the bottle body is too hard, it will affect the patient’s experience and make it resistant to the brand of eye drops. To a large extent, no second purchase will be made. In addition, packaging will also have a certain impact on the reputation of the drug.

In general, LDPE eye drop bottles are more convenient than polypropylene in terms of drug delivery experience, and are favored by many eye drop manufacturers.