Eye drops refer to sterile liquid preparations such as clear solutions or suspensions for eye drops made of medicines and excipients to prevent or diagnose eye diseases. As a kind of sterile medicine, its requirements for eye drop bottles are very strict. Whether the sterilization is thorough is of great significance to the efficacy of the medicine and the health of the patient.
Among many sterilization methods, ethylene oxide sterilization is the most commonly used sterilization method for eye drop bottles. As a broad-spectrum sterilant, ethylene oxide can kill various microorganisms at room temperature, including spores, tubercle bacilli, bacteria, viruses, fungi, etc., mainly destroying the metabolic process of bacteria. This kind of sterilization method does not damage the sterilized items and has strong penetrating power. Most items that are not suitable for general methods can be sterilized and sterilized by ethylene oxide, such as electronic instruments, optical instruments, books, documents, Dialyzers and disposable medical supplies, etc.
Ethylene oxide can be sterilized with 100% pure ethylene oxide or a mixture of ethylene oxide and carbon dioxide, and the use of freon is prohibited. Excessive exposure to ethylene oxide can cause burns and irritation to the patient. Therefore, when using this sterilization method, the residue should also be investigated. The amount of the residue is related to the sterilized article materials, sterilization parameters, packaging materials and sizes, loading capacity, analytical parameters, etc. Related, the measurement method is based on YBB60202012.
Ethylene oxide sterilization is a widely used sterilization method for plastic pharmaceutical packaging materials. The sterilization method used for eye drop bottles depends on the properties of the drug and the specific needs of pharmaceutical companies.
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