What is the ISO15378 quality management system

 The ISO15378 quality management system is an international application standard for pharmaceutical packaging materials. It applies GMP principles and the requirements of the QMS quality management system to the primary packaging materials of pharmaceuticals. Since the primary packaging material is in direct contact with the drug, the GMI principle understood by the organization (enterprise) in the production and quality control of the primary packaging material is very important for the safety of patients when using drugs. The application of GMP for pharmaceutical packaging materials should ensure that these materials meet the needs of the pharmaceutical industry. The key purpose of ISO15378 is to specify a unified requirement for pharmaceutical packaging materials, including some special requirements derived from pharmaceutical GMP production and control.

pharmaceutical packaging

ISO15378

Xinfuda received the ISO15378 quality management system certification issued by the SGS certification body. This indicates that the company has reached international standards in terms of quality management, drug raw material risk control, etc., and will provide more international customers with high-standard and professional services.

paste syringe for dogs supplement

 Probiotic paste available in 30ml and 60ml paste syringe easy to use calibrated syringes. 

When your dog is dyspepsia, you need feed medicine to it. But feeding medicine to dog is difficult, you need think many ideas, like add medicine to dog food, inject medicine to dog's mouth and so on.

dial a dose syringe

Inject medicine to dog's mouth by syringe. Plastic syringe is common in our life, the syringe is one kind of function package. Cause the syringe is not only used to package medicine, also can inject medicine.

Now there has one kind dial a dose syringe, this syringe is easy to use for dog, This syringe has unique structure, it compose of syringe tube, plunger, tip cap, piston, locating ring. The plunger can be printed scale, and match up with locating ring can control the usage amount.

syringe for pets medicine

How to use the oral paste veterinary syringe?

According to the horse condition, confirm the usage amount, then rotate the locationg ring to the confirmed dosage

Insert syringe tip to mouth, then inject medicine.

Must confirm the dog swallow the medicine

COP vial rubber stopper and container tightness test

 A rubber stopper is a commonly used accessory in pharmaceutical packaging, and is generally used with an aluminum cap. The cap of a COP vial used for biological drug packaging is the rubber stopper aluminum cap. Tightness is a very important performance of packaging, so how to detect the tightness of the rubber stopper and the container?

5ml COP vial

100ml COP vial

The tightness of the rubber stopper and the container not only requires the entire packaging system to have good performance under normal pressure, but also requires it to have good air tightness under a certain degree of vacuum to meet the storage of certain negative pressure packaging drugs need. The test method for the tightness of the rubber stopper and the container is as follows:

Take 10 of this product, put it in a beaker, add water for 5 minutes, take it out, dry at 70°C for 1 hour, and set aside. Take another 10 matched COP bottles, add water to the marked capacity, and use the above-mentioned rubber stoppers to close them, and add the matched aluminum caps to press the caps. Put it in a high-pressure steam sterilizer at 121°C±2°C, keep it for 30 minutes, cool to room temperature, and place it for 24 hours. Put the above sample upside down, put it in a co ntainer containing 10% methylene blue solution, place it in a container with an exhaust device, evacuate to a vacuum of 25KPa, maintain for 30 minutes, return the vacuum device to normal pressure, and place it for another 30 minutes. Minutes, take it out, rinse the outer wall of the bottle with water, and observe that the methylene blue solution must not penetrate into the bottle.

The detection of the adhesion between the rubber stopper of the COP vial and the container is of great significance to the safety of the use of the drug. Only by controlling this factor can the stability of the drug during the validity period be ensured.

Why choose Xinfuda veterinary syringe

 Hello, it is a great honor to introduce to you Xinfuda star product-veterinary syringe. This product is mainly used for the treatment of dairy cow mastitis drugs and animal oral administration. This product can improve your product quality and sales, improve your company's economic benefits and production efficiency, and ensure your stable production and supply.

30ml dial a dose syringe

5ml syringe for cow mastitis

This veterinary syringe seal can improve your economic benefits. We also produce syringe seals with scales and positioning rings on the push rod, which can achieve precise drug delivery and reduce waste; our product tubes and caps are rigorously matched, and the sealing performance is good. Leakage, no residue after injection, enhance the efficacy of your product, and then enhance your economic benefits.

This veterinary syringe seal can improve your production efficiency. We can provide different assembly methods according to your drug ingredients and filling methods. After you receive the goods, you can directly fill the products on the high-speed filling machine, saving production time. Provide production efficiency.

Buying this veterinary syringe seal can guarantee your stable production and supply. We have a complete SOP process, from raw materials, workshops, production, quality inspection, release and other aspects of strict control to ensure that your delivery time is worry-free.

We have ISO9001 and ISO15378 quality certificates, CE certification, DMF filing, and EP test reports. Our workshop complies with GMP standards. We have currently exported plastic syringe to more than 30 countries and regions around the world. 

In short, our product is a good opportunity for you to choose, this product can improve your economic efficiency and production efficiency, and ensure your stable production and supply. And in the case of global raw material prices increasing, we can help you provide more solutions. It is definitely your best choice. Looking forward to cooperating with your company.

closure of effervescent vitamin tablets

 Vitamin C effervescent tablet is a solid beverage, which is very popular among young people. A barrel-shaped effervescent tube is selected for the packaging. This type of packaging is different from ordinary medicine bottles. Its characteristics are mainly reflected in the design of the medicine bottle cap.

caps for effervescent tube

FDA-DMF query

Vitamin C effervescent tablets contain effervescent disintegrants, which will quickly disintegrate when placed in water, producing a large amount of carbon dioxide gas. The cap of the effervescent tube is ingeniously designed and consists of a desiccant, a coil spring and an anti-theft ring, which play different roles in protecting the safety and effectiveness of the tablet.

Desiccant is the standard configuration of tablet medicines. Its function is to absorb the moisture inside the bottle and keep the internal environment dry. The desiccant inside the effervescent tube is placed on the top of the bottle cap, which saves space and avoids direct contact between the desiccant and the medicine.

The main function of the spiral spring is to compress the tablets to prevent the effervescent tablet from breaking during transportation and handling, and to protect the integrity of the effervescent tablet. The material is LDPE, which is soft and will not crush the fragments due to excessive pressure.

The design of the anti-theft ring originated from the beverage bottle. When the lid is unscrewed, the anti-theft ring will fall off and stay on the bottle. We can judge whether the effervescent tablet has been opened according to the state of the anti-theft ring, which plays a vigilant role.

The above is the composition and characteristics of the cap of effervescent tube. The desiccant, coil spring and anti-theft ring form a complete cap, which also gives the bottle more functionality to protect the safety of the effervescent tablet.