What is a CRC bottle?

 Child Resistant Caps, also known as CRC (Child Resistant Cap) bottles, are essential packaging for medicines. Safe for families with children, especially babies who can't tell the difference. If the bottle is opened, the child may ingest the tablet by mistake.

28 410 child resistant cap

desiccant cap with crc

child resistant cap

The pharmaceutical packaging child safety cap contains a bottle and a cap. The special design is a double cover, the inner cover and the bottle neck are threadedly connected, and the cover and the inner connecting rod require external force to turn the gland to open. It takes a person to push down and turn to open the bottle. Using advanced injection blow molding, the neck is uniform and the wall thickness is uniform.

Excellent sealing and high safety show good quality. Child-resistant bottles are primarily used in healthcare to prevent children from accidentally ingesting pills or ingesting them.

Introduction to common specifications of amber PET bottles

 Oral liquid preparation is a new type of preparation that combines three dosage forms: decoction, syrup and injection. It has the characteristics of small dosage, good taste, fast absorption, rapid effect, and easy acceptance by patients. Amber PET bottle is a special packaging for this type of preparation. As a kind of pharmaceutical packaging, what are its common specifications?

PET amber bottle

Oral liquid is a sterile or semi-sterile product that is based on traditional Chinese medicine decoction, extracts the active ingredients of the drug, adds additives such as flavoring agents and bacteriostatic agents, and follows the injection ampoule filling process. Oral liquid preparation, therefore also called oral ampoule.

Amber PET bottle is a packaging made of PET as raw material and produced by injection stretch blowing process. This kind of PET raw material has good transparency, light weight, high tensile strength, anti-aging, and resistant to corrosion by most acid and alkali solvents. It is a good raw material for the production of pharmaceutical plastic bottles. The common specifications of amber PET bottles are mainly 60ml and 100ml, which depend on the drugs contained and the actual needs of pharmaceutical companies. Oral liquids are different from tablets in that the dosage is measured in milliliters. Therefore, a small measuring cup is usually provided in the package to facilitate patients to take the medicine. Now it can also be matched with a precision drug delivery device and equipped with oral dosing syringe.

 

28mm child resistant  cap for liquid medicine

5ml oral dosing pipette

10ml oral dosing syringe

The specifications of amber PET bottles are not absolute. 60ml and 100ml are only two common ones on the market. Specific specifications can also be customized according to the requirements of pharmaceutical companies. There are also cases where a drug has multiple specifications at the same time.

Oral dosing syringe: Innovative solutions to improve medication accuracy and convenience

 The oral dosing syringe is a tool specially designed for precise medication administration. It consists of a tube sleeve, a push rod and a medication inner plug. It can effectively replace traditional measuring cups and medication spoons, providing patients with a more accurate way to take medication. The device is suitable for various oral liquid preparations, such as liquid medicines, nutritional solutions and pharmaceuticals.

5ml oral dosing pipette

10ml oral dosing syringe

The sleeve part of the oral dosing syringe is mainly used to hold the medicine, and the pusher part is used to push the medicine into the patient's mouth. The medicine-taking inner plug has a unique design, with a universal diameter of 28mm. It is mainly used to put it into the mouth of the bottle to facilitate the extraction of medicinal liquid.

100ml PET oral liquid syrup bottle

 

28mm child resistant  cap for liquid medicine

The advantages of this device are obvious. It can improve the accuracy and convenience of patients taking medications. Draw an accurate dose of medicinal solution according to the patient's dose. Push the push rod to deliver the medicine accurately into the patient's mouth. With this device, patients can more easily self-administer their medications, avoiding the potential risks of inaccurate dosing. With the continuous development of science and technology, this kind of application in the medical field has broad prospects. In the future, it may play a greater role in precision medicine.

In summary, oral dosing syringes are an innovative solution to improve the accuracy and convenience of taking medication. It can improve the accuracy and convenience of patients taking medications. In the future, this device has broad application prospects in precision medicine and other fields, and is worthy of further exploration and research.

Application of high-density polyethylene bottles in solid pharmaceuticals

 High-density polyethylene bottles (HDPE bottles) are a commonly used plastic packaging that are widely used in pharmaceutical packaging due to their excellent physical and chemical properties. Compared with traditional glass bottles, this bottle has better impact resistance, chemical stability and portability. It has become an important choice in solid pharmaceutical packaging.

medicine bottle

1. Impact resistance: High-density polyethylene bottles can withstand strong impact and are not easily broken. They can effectively protect the internal drugs from the external environment.

2. Chemical stability: It has good stability against a variety of chemical substances and is resistant to corrosion by most acid and alkali solvents at room temperature. It can prevent the interaction between drugs and packaging materials and ensure the quality of drugs.

3. Portability: Bottles made of this material are relatively light, easy to transport and use, and also reduce transportation costs.

4. Good sealing: It has good sealing performance and can effectively prevent drugs from getting damp and contaminated.

5. Moisture-proof performance: Due to the strict requirements for moisture-proof performance of solid drugs, this bottle will have a small medicine bin on the lid to store desiccant and maintain the stability of the internal environment of the package.

The above is the application of high-density polyethylene bottles in solid drugs. Its excellent impact resistance, chemical stability and portability make it a very widely used pharmaceutical packaging.

Precautions when using oral dosing syringe

 For patients who are inconvenient to take oral medications, such as children, elderly people with limited mobility, etc., the oral dosing syringe is a very friendly device. It consists of a tube sleeve, a push rod and an inner plug, which is easy to use and has accurate dosage. When using this device, you need to pay attention to the following issues:

5ml oral dosing pipette

10ml oral dosing syringe

1. Because of the need to come into contact with drugs, in order to avoid contamination of the drugs by external pollutants, operators should disinfect their hands before using the oral dosing syringe to ensure their own hygiene and avoid bringing external bacteria to the patient and affecting their recovery. .

2. When taking medicine, you need to strictly follow the prescribed dosage. Overdosage of medicine can easily increase the burden on the kidneys, and insufficient medicine will not achieve the corresponding therapeutic effect. Both situations are not conducive to the patient's recovery, so we need to calculate in advance before extracting the medicine. Medication dosage. There are clearly marked scales printed on the tube body, and the dosage is accurate, so that we can accurately control the dosage of medicine.

3. The oral dosing syringe is a reusable device. After feeding the patient, we need to clean the device to ensure its hygiene for next use.

100ml PET oral liquid syrup bottle

 

28mm child resistant  cap for liquid medicine

The above are three issues that need to be paid attention to when using the oral dosing pipette. In addition, when using the inner stopper for taking medicine, we must pay attention to matching the inner stopper with the bottle mouth to avoid leakage during the extraction process, causing unnecessary of waste.

What are the characteristics of oral dosing syringe

 Oral dosing syringe is a special medicine feeding tool, which is composed of a tube sleeve and a push rod, and is matched with a medicine taking inner plug, which can replace measuring cups and medicine spoons to accurately feed medicine to patients. It is mainly suitable for various oral liquid preparations. This syringe has the following characteristics:

5ml oral dosing pipette

10ml oral dosing syringe

1. The sleeve is made of polypropylene, and the push rod is made of polyethylene. These two materials have stable performance and are resistant to corrosion by most acid-base solvents to ensure the stability of the drug.

2. It is necessary to strictly follow the prescribed dosage when taking the medicine. Excessive or insufficient is not conducive to the recovery of patients. There is a clear scale printed on the body of the oral drug delivery device, the dosage is accurate, and the dosage of the drug can be precisely controlled.

100ml PET oral liquid syrup bottle

 

28mm child resistant  cap for liquid medicine

3. Drug residue is also a factor that patients are very concerned about when taking drugs, which is related to the usage rate of drugs and the accuracy of drug dosage. The push rod of the applicator fits perfectly with the sleeve, which can greatly reduce drug residues, improve the utilization rate of drugs, and avoid waste.

4. Liquid preparations are easy to waste when extracting the liquid medicine. This device is equipped with an inner plug to facilitate the extraction of the liquid medicine. The diameter of the inner plug is 28mm, which is suitable for most medicine bottles.

On the whole, the oral dosing syringe has the characteristics of stable performance, precise dosage, reduced residue, and convenient operation.

Decolorization test of eye drop bottles

 Eye drop bottles are an important packaging form for ophthalmic drugs. Since they are in direct contact with the eyes, their quality and safety are particularly important. The decolorization test is an important test item in their quality standards.

5ml eye dropper bottle

Eye drop bottles are usually made of low-density polyethylene (LDPE) raw materials, which have excellent physical properties and chemical stability. The decolorization experiment is mainly aimed at packaging with colored plastic materials. Its purpose is to detect whether there is a migration risk of colorants and to avoid contamination of drugs due to migration of colorants, which may affect drug treatment effects and even patient health. Therefore, decolorization experimental testing of packaging containing colorants has become the key to ensuring drug safety.

In the YBB00062002-2015 "Low Density Polyethylene Medicinal Eye Drop Bottles" standard, the operations and requirements for the decolorization test are as follows: Take 50 c of the entire part of the product into 2cmx0.3cm small pieces, and place three stoppered cones respectively. In the bottle, add 4% acetic acid solution (60C+2C), 65% ethanol solution (25C+2C), and n-hexane (25C+2C) 50ml each, soak for 2 hours, and use the same batch of 4% acetic acid solution and 65% alcohol solution. , n-hexane is used as the blank liquid, and the color of the soaking liquid should not be too deep.

In short, eye drop bottles are special packaging for ophthalmic drugs, and their quality and safety are crucial to the efficacy of the drugs and the health of patients. Conducting decolorization tests is an important measure to ensure drug quality and medication safety. It is also an important guarantee to improve product quality and safety and ensure medication safety for ophthalmic patients.