Differences in the design of oral liquid bottle caps for glass bottles and plastic bottles

 In the packaging design of oral liquids, the selection of medicinal bottle caps is crucial. Especially for oral liquid screw caps with child protection function, there are certain differences in the internal design between glass bottles and plastic bottles.

 

28mm child resistant cap for liquid

Background and risks of oral liquids

As a pharmaceutical preparation with good taste, oral liquids are extracted from Chinese herbal decoctions, and additives such as flavoring agents and antibacterial agents are added, and are sealed in bottles in a sterile or semi-sterile form. However, because of its taste close to that of beverages, it is easy for children to mistake it for ordinary drinks, and there is a risk of accidental ingestion. The physiological characteristics of children determine that they have low tolerance for drugs, and excessive consumption may bring serious consequences and even endanger life.

60ml HDPE dry syrup bottle

Design of water-based screw caps

In order to reduce the risk of accidental ingestion of oral liquids, water-based screw caps with child protection function are often used. This cap adopts an inner and outer double-layer structure design, and the inner and outer caps are connected by a card slot. When opening the cap, it is necessary to press down the outer cap and rotate it at the same time to drive the inner cap to rotate together and complete the opening action. This design can effectively prevent children from opening the package at will in a short time, reducing the risk of accidental ingestion.

Differences between glass bottles and plastic bottles

Although the water-based screw-on caps are used in both glass bottles and plastic bottles, there are certain differences in their internal designs. It is mainly reflected in the gasket inside the cap. The gasket of the glass bottle cap is relatively thicker, while that of the plastic bottle is relatively thinner. This difference is mainly determined by the different materials of the bottles. Glass bottles are relatively more brittle, and the increase in the thickness of the gasket can enhance its performance in sealing and pressure resistance, ensuring that the liquid is not easy to leak. Since the material of plastic bottles is relatively soft, the gasket of the cap can be relatively thin, which can ensure the sealing and reduce the production cost at the same time.

The design difference between the oral liquid bottle caps in glass bottles and plastic bottles is mainly reflected in the thickness of the gasket, which is determined according to the material of the bottle body and aims to ensure the good sealing of the bottle. Through reasonable design and selection, the water-based screw-on cap can effectively reduce the risk of accidental ingestion of oral liquid and ensure the safety of children's medication.

Types of medicine cap

 Medicine caps, or pill caps, come in a variety of types depending on their purpose, design, and the type of medication being contained. Here are some common types:

child resistant cap

1. Child-Resistant Caps (CRC)

Purpose: Designed to prevent children from accidentally opening bottles and ingesting the contents.

Mechanism: Typically require a combination of pushing down and twisting to open.

Used for: Prescription medications, over-the-counter drugs, or substances that can be harmful if ingested by children.

 

28mm child resistant  cap for liquid medicine

2. Senior-Friendly Caps

Purpose: Easier to open for elderly people or those with limited hand strength or dexterity.

Design: May be flip-top or have an easy-to-grip design, often with wider threads for better leverage.

3. Tamper-Evident Caps

Purpose: Provide visual evidence if the bottle has been opened or tampered with.

Design: Includes a band around the neck of the bottle that breaks or shows signs of damage when the bottle is opened.

Used for: Prescription medications, supplements, and over-the-counter drugs.

4. Non-Child-Resistant Caps

Purpose: Provide simple, easy access for adults.

Design: Regular screw-on caps without child-resistant features, typically used for non-hazardous substances.

5. Snap-On or Press-On Caps

Purpose: Simple to close and open by pressing the cap firmly onto the bottle.

Design: No twisting required, commonly found in some over-the-counter bottles or small containers.

6. Dropper Caps

Purpose: Allows controlled dispensing of liquid medications, often used for liquids like eye drops or oral syrups.

Design: Comes with a dropper or nozzle to control the amount of liquid dispensed.

Used for: Liquid medications, oils, and tinctures.

7. Flip-Top Caps

Purpose: Often found on liquid medications or products that require frequent opening.

Design: Includes a lid that flips open, providing easy access to the contents without removing the cap entirely.

Used for: Lotions, liquid medications, and some over-the-counter drugs.

8. Pressure-Sensitive Caps

Purpose: Used to maintain an airtight or moisture-proof seal.

Design: Seals tightly with pressure, often used for powders or substances that must remain sealed to retain their potency.

9. Screw Caps

Purpose: A simple screw-on mechanism to seal the bottle.

Design: Used for a variety of products, including vitamins and prescription medications.

desiccant cap

10. Bottle Caps with Desiccants

Purpose: Includes a small desiccant packet or material to absorb moisture and keep the contents dry.

Used for: Pills and tablets that are sensitive to moisture, like certain antibiotics or vitamins.

Different types of caps are designed to ensure that the medications are safe, secure, and convenient for the end user, depending on their needs and the type of medication.

The Innovative Container with Silica Gel Cap: A Game Changer for Product Preservation

 Have you ever opened a box of shoes or a new electronic gadget and found those little packets of silica gel tucked inside? While we often toss those packets aside, they play a crucial role in maintaining the quality and longevity of products. Now, imagine if you could harness that moisture-absorbing power directly in the packaging itself. Enter the innovative container with a silica gel cap-a simple yet revolutionary concept in product preservation!

desiccant cap

What is a Silica Gel Cap?

A silica gel cap is essentially a cap made from materials infused with silica gel, which is known for its excellent moisture-absorbing capabilities. Unlike traditional caps that can trap humidity inside, these specialized caps help regulate moisture levels, preventing mold, mildew, and degradation of the product inside.

Benefits of Using a Silica Gel Cap

Enhanced Shelf Life: For products like pharmaceuticals, cosmetics, and food items, maintaining a stable environment is crucial. For instance, a skincare cream housed in a container with a silica gel cap can remain fresh and effective longer since excess moisture is absorbed, preventing the growth of bacteria and mold.

Cost-Effective: By extending the shelf life of products, manufacturers can reduce waste and save costs associated with returns and replacements. For example, a brand that uses silica gel caps in their vitamin bottles may find fewer expired products on shelves, translating to better inventory turnover.

Environmentally Friendly: Silica gel is non-toxic and can be reused. Some innovative brands are even creating containers where the silica gel cap can be replaced once saturated, promoting sustainability.

User Convenience: For items like pet food, which often spoil quickly due to humidity, a silica gel cap can keep the contents fresher for longer. Imagine being able to open a bag of kibble and find it just as crunchy and appealing as when you first bought it!

effervescent tablet packaging

Real-World Applications

Electronics: Devices like cameras and smartphones are sensitive to moisture. Packaging them with a silica gel cap can help maintain optimal conditions, reducing the risk of damage from humidity.

Pharmaceuticals: Brands that produce sensitive medications, like insulin, can integrate silica gel caps into their packaging to ensure product efficacy over time.

Food and Beverages: Companies like Nestlé are exploring silica gel caps for snacks to keep them crispy longer, ensuring that every bite is as satisfying as the first.

desiccant bottle with silica gel

Conclusion

The container with a silica gel cap is more than just a clever design; it's a practical solution that bridges the gap between effective product preservation and consumer convenience. As we continue to seek sustainable and efficient ways to maintain product quality, these innovative containers may just become the norm across various industries. So next time you come across a silica gel cap, remember—it's not just packaging; it’s preserving the quality of what you love!

The PP28 Oral Liquid Bottle Cap: A Crucial Component in Liquid Medication Packaging

 In the intricate world of pharmaceutical packaging, every component is meticulously designed to ensure the safety, integrity, and effectiveness of the medication it houses. Among these components, the PP28 oral liquid bottle cap stands out as a versatile and essential element. Widely used in the packaging of various liquid medications, this cap plays a crucial role in maintaining the quality and usability of the products. In this blog, we delve into the reasons behind the widespread use of the PP28 cap and its significance in pharmaceutical packaging.

plastic bottle with cap for liqoid medicine

Understanding the PP28 Oral Liquid Bottle Cap

The PP28 oral liquid bottle cap is specifically designed for bottles that contain liquid medications. The "PP" stands for polypropylene, the material used to manufacture the cap, while "28" refers to the 28mm diameter of the bottle neck it fits. This cap is not just a simple closure; it incorporates several advanced features that make it ideal for pharmaceutical applications.

 

28mm child resistant cap for glass liquid

Key Features and Benefits

Child-Resistant Mechanism:

Safety First: One of the paramount concerns in pharmaceutical packaging is preventing accidental ingestion by children. The PP28 cap often includes a child-resistant mechanism that requires a specific combination of pressing and turning to open. This feature ensures that children cannot easily access the medication, providing an added layer of safety.

Tamper-Evident Seal:

Ensuring Integrity: The tamper-evident seal is a critical feature of the PP28 cap. It provides a visual indication if the bottle has been opened or tampered with. This assurance is vital for both consumers and manufacturers, as it guarantees that the medication remains untouched and uncontaminated until it reaches the end-user.

Leak-Proof Design:

Maintaining Sterility: Liquid medications must be kept sterile and free from contamination. The PP28 cap features an airtight seal that prevents leaks, ensuring that the contents remain uncontaminated and preserving the medication's efficacy.

Ease of Use:

User Convenience: Despite its safety features, the PP28 cap is designed for easy opening and resealing by adults. This balance of security and convenience makes it user-friendly, particularly for patients who need to take their medication regularly.

Applications in Liquid Medication Packaging

The PP28 oral liquid bottle cap is utilized across a broad spectrum of liquid medications, thanks to its versatile design and functionality. Some of its common applications include:

Cough Syrups:

Protection and Convenience: Cough syrups are frequently used by both children and adults. The PP28 cap ensures that these medications are safe from tampering and accidental ingestion while providing ease of access for regular use.

Nutritional Supplements:

Preserving Potency: Liquid vitamins and nutritional supplements require secure packaging to maintain their potency. The airtight and leak-proof design of the PP28 cap ensures these supplements remain effective throughout their shelf life.

Prescription Medications:

Ensuring Safety: Prescription liquid medications often come with specific storage and handling requirements. The PP28 cap meets these demands by providing a secure, tamper-evident closure that maintains the medication's integrity.

Conclusion

The PP28 oral liquid bottle cap is a prime example of how thoughtful design and material selection can significantly impact pharmaceutical packaging. Its widespread use across various liquid medications highlights its versatility and effectiveness in ensuring the safety, integrity, and usability of pharmaceutical products. As the industry continues to advance, the PP28 cap will remain a vital component in delivering high-quality, safe, and effective liquid medications to consumers.

What is a CRC bottle?

 Child Resistant Caps, also known as CRC (Child Resistant Cap) bottles, are essential packaging for medicines. Safe for families with children, especially babies who can't tell the difference. If the bottle is opened, the child may ingest the tablet by mistake.

28 410 child resistant cap

desiccant cap with crc

child resistant cap

The pharmaceutical packaging child safety cap contains a bottle and a cap. The special design is a double cover, the inner cover and the bottle neck are threadedly connected, and the cover and the inner connecting rod require external force to turn the gland to open. It takes a person to push down and turn to open the bottle. Using advanced injection blow molding, the neck is uniform and the wall thickness is uniform.

Excellent sealing and high safety show good quality. Child-resistant bottles are primarily used in healthcare to prevent children from accidentally ingesting pills or ingesting them.

Three major factors that affect the size of child resistant cap

 Child Resistant Cap for oral preparations are an important part of pharmaceutical packaging, and they play a very important role in the sealing of the entire packaging. The size of the cap is related to whether it can achieve a good fit with the bottle mouth, which in turn affects the sealing of the packaging. During the production process, the factors that affect the size of the cover mainly include the following three aspects:

28mm bottle cap

child resistant cap

1. Holding pressure and time

As the holding time increases, the weight of the bottle cap gradually increases, resulting in an increase in volume. Similarly, as the holding pressure increases, the weight of the raw material increases in the same period of time, and the weight of the bottle cap increases, which will lead to an increase in volume (increase in size).

2. Cooling time

Regardless of visual analysis or experimental data, as the cooling time of the medicine bottle cap in the mold increases, the temperature of the bottle cap will obviously show a linear decrease. This phenomenon also exists when the lid is cooled after demoulding, but it will take longer to reduce the same temperature. That is to say, within the same period of time, the cooling effect in the mold is far better than the cooling after demoulding.

The cooling rate (°C/min) will affect the density of the cap. As the cooling rate increases, the density of the bottle cap gradually decreases.

That is, as the cooling time increases, the grammage remains unchanged and the density decreases, the volume becomes larger (the size becomes larger).

3. Raw material temperature

As the temperature of the raw material increases, if the cooling time remains unchanged, the temperature of the resulting bottle cap will be higher. After natural cooling after demoulding, the volume will become smaller (the size will become smaller) due to the principle of thermal expansion and contraction. The injection molding equipment parameters corresponding to the raw material temperature include screw temperature and mold temperature.

The above are the three major factors that affect the size of medicinal bottle caps. When producing caps, you should focus on these three aspects of data to ensure the accuracy of the finished product size.

 

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28mm Child Resistant Cap for Liquid and Glass Bottle

Sizes: 28mm 410

Material: HDPE

Cap: child resistant cap

Certificate: ISO9001:2008, ISO15378, CE, DMF

Child resistant cap has been used by customers for drugs ANDA APPROVAL in the United States.

Advantage of our caps of 28mm child resistant cap:

1. Excelling Sealing 2.Child Proof Cap  3.28 410  4.High Standard Quality Inspection 5.Meet ISO15378 and in GMP workshop

B.We have more than 20 years experiences and get ISO15378 Certification, selling well in more than 100 countries.

C.Get free samples until next month!

D.We have enough stock in our storehouse and we are ready to shipping!

For Orders

1. Orders of miaxed item are acceptable

2. Trial order is acceptable

3. Small quantity is acceptable when stock is available

For Shipment

1. For samples, we propose to send by DHL, UPS, FEDEX etc.
   

2. For big orders, we propose to have the goods dispatched by sea or air.

For Lead Time

1. Lead time for samples will be with in 3-7 days.

2. Lead time for MOQ will be with in 10 days after order firmed.

These special features of medicinal bottle caps

 Plastic bottles are a common form of packaging for medicines, generally consisting of a bottle cap and a bottle body. As an important part of packaging, the importance of pharmaceutical bottle caps is becoming more and more prominent. On the basis of ensuring the integrity and sealing of packaging, it also shows a diversified development trend in terms of functions. Below, let's reveal the special functions of medicinal bottle caps together.

medicine cap

Anti-theft ring

This feature is relatively common, inspired by the anti-theft ring on the beverage bottle. A small circle is connected under the bottle cap, which is also called a one-time broken anti-theft ring. When the cap is unscrewed, the anti-theft ring will fall off naturally and remain on the bottle. It can be judged whether the medicine has been maliciously opened according to the state of the anti-theft ring.

anti-theft ring on cap

Key points: Xinfuda's medicinal bottle caps have an anti-theft ring, which automatically falls off after opening, and the connection has passed 300 breakpoint tests, making it easy to open.

Moisture-proof

Solid drugs such as tablets and capsules have strict requirements on the moisture-proof performance of the packaging. In addition to selecting production materials with good barrier properties to prevent external water vapor from invading, the moisture-proof inside the packaging is also important. The moisture-proof cover cleverly uses the space on the top of the cover to design a small medicine compartment to store desiccant and absorb moisture to maintain the stability of the internal environment of the package.

desiccant cap

Key points: Xinfuda’s moisture-proof cover uses imported desiccant, and the moisture content of the finished product is ≤2%, which is higher than the national standard of 2.8; the saturated moisture absorption rate of the desiccant is between 24% and 28%, ensuring that the drug is kept in good condition.

child resistant

This is a more popular type of lid in recent years. It adopts an inner and outer double-layer structure design, and it must be opened by pressing down and rotating at the same time. Such a cover can effectively prevent children from opening the package at will and accidentally eating medicines.

28mm child resistant cap

Key points: Xinfuda's child-proof cap adopts a universal 28 mm, which can be adapted to plastic bottles or glass bottles. According to the different characteristics of the two materials of plastic and glass, a corresponding special design has been made on the internal structure of the bottle cap, and the sealing effect is excellent. better.

At present, the special functions of medicinal bottle caps include three aspects: moisture-proof, child-proof and anti-theft. With the continuous changes in market demand, the design of the caps is also constantly updated and iterated. We will wait and see what special functions will be added in the future. Xinfuda will also do more explorations on the function of the lid to provide better security for the drug.

Different functions of medicinal bottle caps

 Pharmaceutical bottle caps are an important part of plastic bottles and play a vital role in the overall airtightness of packaging. With the continuous change of market demand, the functionality of the cap also presents a diversified development trend.

 

28mm child resistant  cap for liquid medicine

Desiccant cap: a bottle cap with moisture-proof function. It uses the space on the top of the cap to design a small medicine compartment to store desiccant to achieve moisture-proof effect. This design reduces the direct contact between the drug and the desiccant, and is suitable for tablet packaging of larger dosage forms, such as effervescent tablets, and can also be used for test strip packaging. There is also a cover that adds a coil spring on this basis to compress the tablet.

effervescent tube cap

Child Resistant Cap: a safety cap with a childproof function. It adopts an inner and outer double-layer structure design, and the interior is connected by a card slot. If the lid is opened, the outer layer cap needs to be pressed down, and the inner layer cap is driven to rotate at the same time. Such an opening method involves applying force in two directions, which can improve the safety of the bottle and prevent children from opening the package at will and accidentally eating the medicine. For solid packaging and liquid preparation packaging, the lids are slightly different in design, but there is no difference in function.

Moisture-proof cap with CRC: On the basis of press-spin, the moisture-proof function is added. The small drug compartment on the top of the medicinal bottle cap is used to store the desiccant to avoid direct contact between the drug and the desiccant. It is suitable for tablets, capsules and other drugs that require moisture-proof storage.

desiccant cap

The above are the different functions and applications of medicinal bottle caps. As a provider of overall functional packaging solutions, Xinfuda supplies various types of pharmaceutical bottle caps. For special needs, we can also provide exclusive customized services to meet your diverse needs.

Different functions of medicinal bottle caps

 Pharmaceutical bottle caps are an important part of plastic bottles and play a vital role in the overall airtightness of packaging. With the continuous change of market demand, the functionality of the cap also presents a diversified development trend.

 

28mm child resistant  cap for liquid medicine

Desiccant cap: a bottle cap with moisture-proof function. It uses the space on the top of the cap to design a small medicine compartment to store desiccant to achieve moisture-proof effect. This design reduces the direct contact between the drug and the desiccant, and is suitable for tablet packaging of larger dosage forms, such as effervescent tablets, and can also be used for test strip packaging. There is also a cover that adds a coil spring on this basis to compress the tablet.

effervescent tube cap

Child Resistant Cap: a safety cap with a childproof function. It adopts an inner and outer double-layer structure design, and the interior is connected by a card slot. If the lid is opened, the outer layer cap needs to be pressed down, and the inner layer cap is driven to rotate at the same time. Such an opening method involves applying force in two directions, which can improve the safety of the bottle and prevent children from opening the package at will and accidentally eating the medicine. For solid packaging and liquid preparation packaging, the lids are slightly different in design, but there is no difference in function.

Moisture-proof cap with CRC: On the basis of press-spin, the moisture-proof function is added. The small drug compartment on the top of the medicinal bottle cap is used to store the desiccant to avoid direct contact between the drug and the desiccant. It is suitable for tablets, capsules and other drugs that require moisture-proof storage.

desiccant cap

The above are the different functions and applications of medicinal bottle caps. As a provider of overall functional packaging solutions, Xinfuda supplies various types of pharmaceutical bottle caps. For special needs, we can also provide exclusive customized services to meet your diverse needs.

Application of medicinal bottle cap in cough syrup medicine

 As an important part of medicinal plastic bottles, the medicinal bottle cap plays an important role in ensuring the stability of the drug. As people's attention to children's safety increases, plastic cap is not only used in solid drug packaging, but also in oral liquid drugs such as cough syrup.

 

28mm child resistant  cap for liquid medicine

Cough syrup is mainly used for relieving cough and reducing phlegm. It is suitable for colds, coughs, phlegm, bronchial asthma and other diseases. It is a prescription drug. In the selection of cough syrup, it is easy for children to accept cough syrup because of its sweet taste. It is precisely for this reason that children mistake medicines for beverages, and incidents of accidental ingestion of medicines emerge in endlessly, endangering children's safety.

desiccant cap

Medicinal l bottle cap is a cap with a special structure, which is composed of an inner and outer double-layer structure. The packaging cannot be opened only by rotating the outer cap. It must be rotated while pressing down the outer cap to open. Such an opening method is difficult for children, so that children can be prevented from opening the package arbitrarily, and accidents of eating medicines by mistake can be avoided.

child resistant cap

In fact, the United States, Australia and other countries have already enacted legislation to force the use of this kind of packaging for toxic drugs, which is also to better protect the safety of children. In China, many pharmaceutical companies have already adopted this kind of packaging. In short, this form of cover will be a big trend in the future.

The innovative design of oral liquid bottle cap

 The cap is an important part of the medicinal plastic bottle, which mainly plays the role of sealing. With the continuous changes in market demand, the functionality of the cap is also more diversified. For example, the oral liquid bottle cap adopts an innovative design on the basis of airtightness, so that it has the function of preventing children from opening, reducing the risk of children ingesting medicines by mistake.

 

28mm child resistant  cap for liquid medicine

Oral liquid is a sterile or semi-sterile oral liquid, which is based on traditional Chinese medicine decoction, extracts the active ingredients in the drug, adds flavoring agents, bacteriostatic agents and other additives, and is processed by filling and sealing injection ampoules. Liquid preparations. The pharmaceutical packaging is generally dominated by plastic bottles or glass bottles, and the lids are mostly ordinary plastic bottle caps. In order to improve the sealing performance, aluminum foil gaskets are used to seal.

Oral liquid tastes better and is easily accepted by patients, especially children. However, children are in the growth and development period and are full of curiosity about many things. It is easy to mistake the oral liquid for a drink, resulting in accidental ingestion. The press-and-screw oral liquid bottle cap adopts an inner and outer double-layer structure. It cannot be opened only by rotating the cap. It must be rotated while pressing down to open. Such an opening method involves the simultaneous application of force in two different directions, which is difficult for children, which can prevent them from easily opening the package in a short period of time and avoid accidental ingestion of medicines.

Rotational medicine caps are not only used in the packaging of liquid preparations, but are also widely used in solid pharmaceutical plastic bottles such as tablets and capsules. The functionality of the lid is well used.

Definition of medicine bottle extract

 The most common oral solid dosage forms are capsules and tablets, and oral powders and granules for reconstitution are also included in this group of dosage forms. The risk of interaction between packaging components and oral solid dosage forms is generally considered to be low, however, after reconstitution of powders in commercially available containers, there is a possibility of interaction between packaging components and the reconstitution liquid. Compared with the contact time between the components and preparations of liquid matrix oral preparations, although the contact time is relatively short, some considerations need to be taken into account for the evaluation of the compatibility and safety of the medicine bottle.

45ml plastic medicine bottle with CRC

50ml desiccant bottle

A common medicine bottle is a plastic bottle with a twist or pull switch, usually a high-density polyethylene bottle or other flexible packaging, such as a pouch or blister pack, and the cap and inner seal of the pouch liner is a common Seal combination. If fillers, desiccants and other absorbent materials are used, they are also considered inner packaging components.

effervescent packaging

medicine cap

Oral solid dosage forms generally need to avoid the potential adverse effects of water vapor, as well as irradiation and reactive gases. For example, the presence of moisture may affect the decomposition rate of the active pharmaceutical ingredient or the dissolution rate of the preparation, so the container should choose a material with a low water vapor transmission rate, and the container closure system should be sealed to protect the drug product. USP has established 3 standard test methods for water vapor transmission rate for oral solid dosage forms.