Protecting the stability of drug efficacy: moisture-proof design of effervescent tube

 In modern pharmaceutical packaging, moisture resistance is one of the most important considerations, especially for special packaging forms such as effervescent tubes for oral solid drugs. The moisture resistance of effervescent tubes depends not only on the design of the internal desiccant, but also on the strict requirements of the packaging material - white paper.

Effervescent tube

The desiccant inside the effervescent tube cap is mainly composed of a mixture of silica gel and molecular sieves. This design ensures long-term and effective control of the number of water molecules. Silica gel can continuously and stably absorb moisture, while molecular sieves quickly absorb moisture in a short time. Together, they ensure that the stability and effectiveness of the drug are not affected by the humid environment.

The key is that the desiccant is sealed by white paper, which must meet strict national standards, such as moisture content less than 6%, no arsenic more than 0.0001% and no lead more than 0.0005%. These requirements ensure the high quality and stability of white paper, and avoid the barrier effect of excessively thick paperboard or excessive moisture content affecting the performance of the desiccant.

The manufacturing and quality standards of the effervescent tube follow the national standard YBB00172004-2015 "Oral Solid Medicinal Low-density Polyethylene Moisture-proof Combined Bottle Cap", in which the specifications of the white paper are strictly controlled at 0.46-0.55mm pure high-quality wood pulp white cardboard to ensure that the drug contact surface has no flake fluorescence after inspection under ultraviolet light.

caps for effervescent tube

The effervescent tube performs well in protecting the stability of drug efficacy. The key to its moisture-proof performance lies in the high-quality white paper material and precise desiccant design. This high-standard manufacturing process not only ensures the safety of drugs during storage and transportation, but also sets a good example for the development of modern pharmaceutical packaging technology.

Xinfuda Unveils Innovative Multifunctional 28mm Cap: CRC and Desiccant Cap

 Shijiazhuang, China – Xinfuda Medical Packaging, a global leader in advanced packaging solutions, proudly announces the launch of its latest innovation: the multifunctional 28mm cap. This new cap combines the features of a child-resistant closure (CRC) with an integrated desiccant, setting a new standard in packaging technology for pharmaceuticals and other sensitive products.

28mm Silica Gel Cap with Child Resistant

 

Dual-Functionality for Enhanced Safety and Preservation

The multifunctional 28mm cap is designed to address two critical needs: child safety and product preservation. The child-resistant feature ensures that medications and other potentially hazardous substances are kept out of reach of children, significantly reducing the risk of accidental ingestion. The integrated desiccant, on the other hand, protects the contents from moisture, maintaining the integrity and efficacy of the product over time.

Innovative Design and Material Excellence

Crafted from high-quality, durable materials, Xinfuda's new cap is engineered for reliability and longevity. The cap's design not only ensures a tight seal to prevent contamination but also incorporates a user-friendly mechanism that makes it easy for adults to open while remaining secure against tampering by children. The built-in desiccant is seamlessly integrated, providing continuous moisture protection without the need for additional packaging components.

Versatility and Wide Application

The 28mm multifunctional cap is suitable for a wide range of applications, including pharmaceuticals, nutraceuticals, and other moisture-sensitive products. Its versatility makes it an ideal solution for manufacturers looking to enhance the safety and shelf life of their products. By combining CRC and desiccant functions in a single cap, Xinfuda offers a streamlined, cost-effective packaging solution that meets the highest standards of safety and quality.

Commitment to Innovation and Quality

Xinfuda's introduction of the multifunctional 28mm cap underscores its commitment to innovation and excellence in the packaging industry. The company continues to leverage cutting-edge technology and advanced materials to develop products that meet the evolving needs of its clients and the regulatory landscape.

Conclusion

With the launch of the multifunctional 28mm cap, Xinfuda Medical Packaging once again demonstrates its leadership in providing advanced, reliable, and user-friendly packaging solutions. This new cap is poised to make a significant impact on the industry by enhancing product safety and longevity, ultimately benefiting manufacturers and consumers alike.

What are the inspection items for eye drop bottles

 As an important tool for eye medication, the quality of eye drop bottles is directly related to the user's vision health and safety. According to the standard YBB00062002-2015 "Low-density polyethylene eye drop bottles", the inspection items of eye drop bottles include the following:

eye drop bottles

Appearance and identification: The eye drop bottle must first have an intact appearance without obvious foreign matter or defects. At the same time, the uniqueness and identifiability of the product are ensured through labeling and packaging to avoid confusion.

Density and sealing: The density test of the eye drop bottle ensures that the bottle material meets the requirements, while the sealing test ensures that it does not leak during use to avoid contamination and waste of the liquid medicine.

Drip volume and visible foreign matter: The accurate control of the drip volume directly affects the dosage of the liquid medicine, while the detection of visible foreign matter eliminates any impurities that may affect the clarity and safety of the liquid medicine.

Dissolution test: Including the detection of clarity, pH change, oxidizable substances, heavy metals, absorbance and non-volatile substances to evaluate the stability and safety of the liquid medicine in the bottle.

Ignition residue and n-hexane non-volatile matter: Ensure the compliance of the residue after the bottle is burned under specific conditions, and exclude the possible contamination of the non-volatile matter on the liquid medicine.

Decolorization test and microbial limit: The decolorization test detects the effect of the bottle material on the photostability of the liquid medicine, and the microbial limit ensures the sterility of the bottle before and after use.

Biological test: Biological tests include abnormal toxicity and eye irritation tests. The abnormal toxicity test ensures that the bottle material will not have adverse reactions or toxic effects on the human body; the eye irritation test evaluates the irritation reaction that may be caused by the liquid medicine contacting the eyes.

Through the above series of strict testing items, the manufacturers and users of eye drop bottles can ensure the quality and safety of the products, thereby effectively ensuring the effect of eye drug administration and the health of users. These testing items not only meet the requirements of the standards, but also reflect the high requirements and challenges of pharmaceutical processes and technologies, providing reliable protection for eye health.