Treatment of dairy cow mastitis with syringe

 Mastitis is a frequently-occurring disease in the dairy cow breeding process, the main cause of which is the invasion of pathogenic bacteria, such as trauma and poor milking techniques. Poor environmental sanitation, improper feeding and management, hormone imbalance, breast defects, etc. The use of veterinary syringe to treat cow mastitis is a commonly used treatment method at home and abroad.

5ml syringe for cow mastitis

The pathogenic microorganisms of dairy cow mastitis are more complex, including more than 80 kinds of bacteria, fungi, mycoplasma, yeast and viruses. In general, Staphylococcus, Streptococcus and Escherichia coli account for more than 70% of clinical mastitis, followed by Corynebacterium pyogenes, Pseudomonas aeruginosa, Necrobacterium, Nocardia, Klebsiella and so on. Asymptomatic recessive mastitis is higher than clinical mastitis, with an incidence of about 50% of the entire herd. About 90% of recessive mastitis is caused by Streptococcus and Staphylococcus.

Mammary perfusion, also known as local drug delivery, is a commonly used treatment method for cow mastitis at home and abroad. The method uses a syringe to inject medicinal liquid into the diseased breast area, so that the medicine directly acts on the pathogenic area or the diseased part in the breast area. Various types of mastitis.

The specifications of intramammary syringe are mostly 5ml, 8ml, and 10ml. The needle is made of soft LDPE raw material, which can reduce the discomfort caused to the cow during administration. The thinner tip can pierce the udder of the cow to complete the administration.

Twin chamber measuring bottle

 The twin chamber measuring bottle is conversation to measure liquid,this bottle has unique measure chamber,so this bottle can instead of measuring cup.This 500ml double neck bottle has two chambers, one for storing and the other for measuring exact doses. The second chamber is designed to eliminate additional measuring by providing precise pouring every time. 

twin neck bottle

You can use twin chamber measuring bottle to dispense a measured amount of liquid,such as pesticides, soaps, lubricants, and concentrated cleaners.

These unique bottles have a large section for your main liquid that can be "squeezed" into a smaller section for easy measurement.  Both necks accommodate the same cap or closure

Two common materials for medicinal bottle cap

 Pharmaceutical bottle caps are an important part of pharmaceutical packaging and play a vital role in the overall sealing of the packaging. There is no doubt about the importance of the lid. There are various types of lids on the market. What are the main materials commonly used?

28mm child resistant cap

sprial cap

In terms of material, there are two common raw materials for medicinal bottle caps: polypropylene and polyethylene. Most of the lids are mainly made of polypropylene, which is a colorless, odorless, non-toxic, translucent solid substance with a temperature range of -30 to 140 °C. It is resistant to corrosion by acid, alkali, salt solution and various organic solvents below 80 °C. Bottles produced with this material are glossier, but less flexible.

Polyethylene is a thermoplastic resin obtained by polymerization of ethylene. It is odorless, non-toxic, feels like wax, has excellent low temperature resistance (minimum operating temperature can reach -100~-70°C), and has good chemical stability. Resistant to most acids and bases (not resistant to oxidizing acids). It is insoluble in common solvents at room temperature, with low water absorption and excellent electrical insulation. The lid of this material is used more in the packaging of effervescent tablets, and its soft characteristics are very suitable for spring lids.

On the whole, the commonly used materials for medicinal bottle caps are mainly polyethylene and polypropylene. Both materials have good stability. The difference lies in flexibility and temperature resistance. The specific material selected depends on the material of the packaging itself. It depends on the actual application.

Introduction of EO Sterilization for Pet Injection Bottles

 Pet injection bottle is a kind of pharmaceutical packaging. In order to prevent the microbes on the packaging from contaminating the vaccine, this packaging needs to be sterilized and can only be used after reaching the microbial limit. Ethylene oxide sterilization is a common sterilization method for this type of packaging.

250ml PE plastic vaccine bottle

Ethylene oxide is also called ethylene oxide. It is a colorless liquid at low temperature with aromatic ether smell. Its boiling point is 10.8 °C, its odor threshold is 760 mg/m~1064 mg/m, and its density is 1.52; it is flammable and explosive, and its maximum The low combustion concentration is 3%. Ethylene oxide does not damage sterilized items and has strong penetrating power, so most items that are not suitable for sterilization by general methods can be sterilized and sterilized with ethylene oxide. For example, electronic instruments, optical instruments, medical instruments, books, documents, fur, cotton, chemical fibers, plastic products, wood products, ceramics and metal products, endoscopes, dialyzers and disposable medical supplies, etc. One of the low temperature sterilization methods.

It is generally believed to be due to its non-specific alkylation with microbial proteins, DNA and RNA. EO can undergo alkylation with free carboxyl, sulfhydryl and hydroxyl groups on proteins, and replace unstable hydrogen atoms to form compounds with hydroxyethyl radicals. Reactive groups required in basic metabolism hinder the normal chemical reactions and metabolism of bacterial proteins, resulting in the death of microorganisms on pet injection vials.

The above is an introduction to the commonly used sterilization methods for pet injection bottles. Ethylene oxide sterilization is a mature sterilization method. Although it has a strong sterilization effect, there are many factors affecting its sterilization, such as concentration and temperature. sterilization effect.

Introduction of three functions of medicinal bottle caps

 Medicinal caps are an important part of plastic bottles and play a vital role in protecting the safety of medicines. In our common lids, it mainly plays three roles:

Sealing: Sealing is the basic function of medicinal bottle caps. The standard size and bottle mouth interference fit to achieve the purpose of blocking the intrusion of external gases or impurities, and prevent the drug from being polluted by the external environment.

28mm child resistant cap

desiccant cap

child resistan cap

Moisture-proof: This function is mainly reflected in the packaging of solid medicines such as tablets and capsules. These medicines contain starch, adhesives and other ingredients, which are prone to deliquescence and adhesion after being exposed to moisture, so packaging with moisture-proof performance is required. Some packaging cleverly uses the space at the top of the medicinal bottle cap, and combines the desiccant with the cap to make a moisture-proof cap to maintain the stability of the internal environment of the packaging.

Child-proof opening: This is also a popular type of lid in recent years. It adopts the design of double-layer structure inside and outside, and must be opened by pressing down and rotating at the same time. Such a cover can effectively prevent children from opening the package at will and accidentally ingesting the medicine.

The above is the introduction of three common functions of medicinal bottle caps. Among them, sealing is the basic function, moisture-proof is mainly used for solid drugs, and the child-proof opening function is suitable for both liquid drugs and solid drugs. These two functions can be independent, or they can appear at the same time, combining the functions of both.

Quality requirements of cardboard of effervescent tube cap

 The effervescent tube is composed of tube body, bottle cap frame, desiccant, spring, cardboard, etc. It is a kind of medicine packaging with very good moisture-proof function. The quality of the packaging is related to the stability and safety of the drug. In addition to the overall quality standard requirements for the packaging, the cardboard must also meet the quality requirements.

144mm effervescent tube packaging

Cardboard is an important part of the bottle cap. It is attached to the top of the bottle cap and acts as a sealing part of the desiccant compartment to isolate the desiccant from direct contact with the drug. Cardboard is the part that is in direct contact with the effervescent tablet, and its composition, thickness, moisture content, etc. will affect the storage of drugs or the moisture-proof performance of packaging. For example, the function of cardboard is mainly to block and seal. Too much thickness will affect the performance of the desiccant, and too high moisture content will easily make the drug damp, stick, and deteriorate.

92mm*21mm plastic tube for tablets

The quality requirements for effervescent tubes are the national standard of YBB00172004-2015 "Oral Solid Medicinal Low Density Polyethylene Moisture-Proof Combination Caps". The lead content should not exceed 0.0005%, and the drug contact surface should be inspected under ultraviolet lamps with wavelengths of 365mm and 254mm, and there should be no flake fluorescence. The thickness is recognized as 0.46-0.55mm pure high-quality wood pulp white cardboard in the industry.

The above are the quality requirements of effervescent tubes for cardboard. A high-quality effervescent tablet packaging not only has strict requirements on raw materials, components, and sealing, but also the moisture content of desiccant and short-term moisture absorption rate must meet the standard requirements, so as to ensure the drug Stability and safety during the validity period.

Application of double neck bottle in equine joint supplement

 Double-neck bottles are generally made of polyethylene, polypropylene or high-barrier raw materials, after adding organic solvents, they are processed by injection blowing, injection molding, extrusion blowing and other processes. This packaging container has very good barrier properties and is used for the packaging of various solutions such as disinfectants and fishing medicines. In addition, double-mouthed bottles are also used as packaging for equine joint supplements.

100ml twin neck bottle

500ml double neck bottle

Equine Joint Supplement is a one-of-a-kind supplement formulated with a balance of glucosamine hydrochloride and chondroitin sulfate, powerful antioxidants to support the overall health of your ungulate friend, this solution is ideal for high performance Active horses required.

Equine joint supplements are typically mixed with Furukawa rations or using oral dosing syringes and fed to horses. The water bottle used to store horse joint supplements adopts the design of two bottle mouths, each bottle mouth corresponds to different functions, one is a quantitative bottle and the other is a volumetric bottle. The volumetric flask is used to store the medicine, and the quantitative bottle is used to measure the volume of the medicine, and the two are connected by a conduit. When using, first open the cap of the quantitative bottle, gently squeeze the bottle with your hand, and the solution will reach the quantitative bottle through the catheter until the desired dose is obtained. Such packaging eliminates the need to pour out the drug for measurement, making the drug delivery process more convenient.

The above is the application of double-necked bottles in equine joint supplements. Thanks to the special design and function, this packaging is also applied to the packaging of solutions that need to be diluted, such as animal anthelmintics.

Application Inventory of COP Bottles

 COP bottle is a plastic packaging container processed from cyclic olefin polymer. It has high transparency, low protein adsorption and high impact resistance, and is a packaging with outstanding functionality. Mainly used in the following drugs:

5ml COP vial

1. High value-added drugs: high value-added drugs have very high value, such as lymphocyte anti-epidemic, hormone drugs, anesthetic drugs, and drugs with accurate dosage requirements. These drugs have higher requirements on packaging. Breakage will result in significant losses. The COP bottle has high impact resistance, which can keep these medicines safe.

2. Drugs with high pH value: When the pH value of the drug is greater than 9, inorganic substances may be precipitated from the glass packaging, bringing the possibility of delamination, and bringing huge risks to intravenous injection products and intramuscular injection products. The COP bottle has stable physical and chemical properties, can tolerate drugs with a pH value greater than 9, and maintain the stability of the drug.z

3. Protein drugs: Protein drugs refer to protein products with certain biological activities, including animal and plant sources and applied biotechnology research and development, which are used to prevent and diagnose human, animal and plant diseases. Protein drugs are easily adsorbed on the glass surface, resulting in waste of drugs. Cyclic olefin polymer raw materials have low protein adsorption properties, which can improve the utilization rate of drugs.

COP bottles are mainly used for the packaging of the above drugs. Of course, in addition to being used as drug packaging, it can also be used for the storage of medical and aesthetic products, such as hyaluronic acid.