28mm cap with deiccant or without desiccant application in pharmaceutical

 In the pharmaceutical industry, the use of 28mm caps with or without desiccants is determined by the specific requirements of the medication being packaged. Here's a breakdown of the applications and considerations for each:

28mm Silica Gel Cap with Child Resistant

28mm Cap with Desiccant Applications:

Moisture-Sensitive Medications: Medications that are hygroscopic or sensitive to moisture require protection to maintain their efficacy and stability. This includes certain tablets, capsules, and powders.

Extended Shelf Life: Products that need an extended shelf life benefit from the moisture absorption properties of desiccants, preventing degradation over time.

Biopharmaceuticals: Some biological products, which are often sensitive to environmental conditions, might also use desiccant caps.

Considerations:

Material Compatibility: The desiccant must be compatible with the pharmaceutical product and the packaging material.

Regulatory Compliance: Desiccants used in pharmaceutical packaging must meet regulatory standards for safety and efficacy.

Cost: Desiccant caps are typically more expensive due to the additional materials and manufacturing processes involved.

 

28mm child resistant cap for liquid

28mm Cap without Desiccant Applications:

Non-Hygroscopic Medications: Products that are not sensitive to moisture do not require desiccants. This includes many liquids, non-hygroscopic tablets, and some ointments.

Short-Term Use: Medications that are intended for short-term use or have a rapid turnover may not need the added protection of a desiccant.

Moisture-Resistant Formulations: Some medications are formulated to be inherently resistant to moisture, negating the need for additional desiccants.

Considerations:

Cost-Effectiveness: Caps without desiccants are generally cheaper to produce and purchase.

Simplicity in Packaging: Simplifies the packaging process and reduces potential compatibility issues with desiccant materials.

Environmental Impact: Reduces the use of additional materials, which may be beneficial from an environmental perspective.

Decision Factors

Moisture Sensitivity of the Product: Determine if the medication degrades or loses potency when exposed to moisture.

Shelf Life Requirements: Assess how long the product needs to remain stable on the shelf.

Storage Conditions: Consider the typical storage conditions (temperature and humidity) the product will be exposed to.

Cost-Benefit Analysis: Weigh the costs of using desiccant caps against the potential benefits of increased product stability and shelf life.

Regulatory Requirements: Ensure compliance with all relevant pharmaceutical regulations and guidelines for packaging.

Summary

Using 28mm caps with desiccants is essential for moisture-sensitive medications to ensure their stability and efficacy over time. For products that are not affected by moisture, caps without desiccants are a cost-effective and simpler option. The decision should be based on the specific needs of the pharmaceutical product, considering factors like moisture sensitivity, shelf life, storage conditions, cost, and regulatory requirements.

Effervescent Tube with Spiral Desiccant Closure

 The spiral desiccant closure or stoppers for our effervescent tablet tubes provide maximum protection while enhancing the shelf life of your product. Our spiral desiccant closure comes with an inbuilt tamper evident ring which can protect the integrity of your product while the spiral design of spiral desiccant cap helps in keeping the product in place during transportation.

spiral desiccant closure

As the industry level of misconduct and OTC drugs introduced the New Deal, industry demand for pharmaceutical packaging will be toward a more secure, more convenient, faster and more environmentally friendly direction. At present, the majority of drug packaging, quality generally unstable, with function of moisture-proof and deoxidizer function of medicinal plastic moisture proof cover less plastic bottles, nearly 7 compounds packaging are not up to international standards. Most domestic pharmaceutical packaging enterprise does not pay attention to technology and new materials research and development, still less investment in technology. Overall packaging materials of low value-added products, pharmaceutical packaging in the international market accounted for 30% of the value of the drug, compared with only 10% in China, far behind the international market.

effervescent packaging

As consumers purchasing trend gradually increase, medical market is more and more big, the pharmaceutical packaging market by the glass to plastic products, plastic pharmaceutical packaging more attention and concern. Pharmaceutical companies appearance of packaging, packaging design and packaging, quality promotes gradually, OTC drugs is more outstanding.

According to this situation, shijiazhuang Xinfuda Medical Packaging co., LTD., a new development with spiral desiccant closure has produced for oral solid pharmaceutical plastic bottles, desiccant cap is more security and prevent children open the auxiliary function, good sealing, in line with the national drug packaging materials and containers registration certificate, without aluminum foil sealing.

Spring on the lid of the effervescent tube

 Effervescent tablets originate from abroad and are popular among young people for their diverse tastes and unique taste. Effervescent tablets contain disintegrating agents, which will produce a lot of carbon dioxide when placed in water. The effervescent tube containing the effervescent tablet is also special, mostly tubular. Many people may have noticed that there is a spiral spring on the lid of the package. So what is the magical effect of this cap spring?

spiral cap

The prescription of an effervescent tablet consists of the main drug, diluent, binder, disintegrant, lubricant and other auxiliary materials. The diluent, binder, lubricant and other auxiliary materials used are the same as ordinary tablets. The appropriate variety should be selected according to the preparation process. Due to the particularity of tablets, effervescent tablets packagingrequirements, and moisture resistance is the most basic requirement. In addition, the effervescent tube is specially designed on the lid. The spiral spring made of LDPE material can compress the tablets in the bottle to prevent them from being broken due to the impact of bumps during transportation, which reduces unnecessary loss. The LDPE material has good flexibility. The use of this material as a coil spring will neither crush the fragmentation agent due to the too hard texture, nor cause the medicine to be poorly fixed due to the too soft texture and too small pressure. The spring design can be maximized the advantages.

With the popularity of effervescent tablets at home and abroad, higher requirements have been placed on pharmaceutical packaging. Nothing is immutable, not only the coil spring, but the small medicine warehouse and anti-theft ring on the bottle cap are the products of industry innovation. With technological innovation and the continuous advent of various new materials, it is believed that the effervescent tube will have a greater improvement in function, and the safety and practicality of the product will be better reflected.

Plastic tube for effervescent tablets

 

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Plastic tube for effervescent tablets

Size: Hight: 92mm Diameter:21mm

Tablet number: 10 tabs 

Material: PP Tube & PE cap

Cap:Spiral cap with desiccant

Desiccant Composition: Silica gel, molecular sieve or the mixture

Certificate: ISO9001:2008  DMF

Xinfuda effervescent tablet tube is made of tube and desiccant cap, desiccant cap contain silica-gel desiccant. Silica-gel desiccant is the only one meet food and through FDA and healthy for human. Silica-gel desiccant can keep tablet away from moist and stay in a dry storage, which is mainly used for effervescent tablets, vitamin C tablets or chew.

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Functional Packaging Supplier

1.The desiccant finished product has a 

moisture content lower than 2%.

2.Desiccant saturated moisture 

absorption between 24% and 26%

 3.Maintain good preservation of the drug

1.Sealing test: Sealed negative pressure 

instrument, under 40Kpa, 2minutes

2.Result: There's no water in the bottle 

or there's no bubbles

          

1.Germany imported automatic 

desiccant filling equipment

2.Dose precision is more conducive 

to control, batch product stability

1.Printing: Custom calibrations,

decorating, and labeling available

2.Filling way: From tip or bottom on 

the tube is ok, which can meet 

pipeline filling with machine

Which May Cause Desiccant Tube Date Error

 The reason of desiccant tube date error has been confiromed. Confirmation is not laboratory test error caused by excessive, is indeed the quality of products after exceeding the standard. The investigation phase of exceeding standard is transferred from the quality control laboratory to the production related department, and the reasons can be divided into the following three kinds:

effervescent packaging

First, deviation of non production process: deviation of test results caused by operator's failure to operate equipment or wrong material.The deviation is investigated by professionals in the quality department, the production department or the equipment management department.

sprial desiccant  closure

Second, production process deviation refers to the deviation of the inspection results caused by the defects of the production process, even if the personnel operation, equipment and materials are correct. The deviation should be investigated by professionals familiar with and familiar with the process technology.

the produce process for desiccant tube

Third, if the material itself brings the deviation, the survey is divided into two cases: first, the factory inspection deviation. First of all by the quality department and supply department investigation, receiving temporary process if there is deviation, the absence of such a material manufacturer shall notify the investigation of its production and storage process without bias, and investigate whether there is any deviation in the transport process.The two is if the factory inspection qualified, in the use or storage process deviation, should be the quality department and supply department investigation storage conditions and weighing process whether there is deviation.

The data record is clear, do not do well documented, product appearance, desiccant tube manufacturers can gain a foothold in the messy. 

How Can Plastic Vitamin Tube Keep Dry Environment

Plastic vitamin tube is used in vitamin tablet packaging due to its dry environment. There are silical-gel desiccant and large molecular sieve desiccant in plastic vatimin tube. However, silica-gel desiccant is the only one through FDA and healthy for human.

spiral desiccant closure

Silica-gel desiccant in vitamin tube is a highly active adsorbent material, which belongs to amorphous material. Silic-gel desiccant of vitamin tube cap insoluble in water, non-toxic and tasteless, chemically stable. According to diameter, silica can be divided into macroporous silica gel, coarse - hole silica gel, type B silicone, fine - hole silica gel. Silica can reuse through rebirth. The main ingredient of silica-gel desiccant is Sio2, for more translucent amorphous, composed of natural mineral processed granular or bead, usually after treatment with sulfuric acid to form, its hard, non-toxic, tasteless, non-corrosive, good chemical stability and thermal stability.

plastic vitamin C tube

Silica-gel desiccant of vitamin tube covers many hydroxyl groups with strong hydrophilicity, at the same time, the surface of silica gel desiccant has many small holes that are not visible to the naked eye, so that its surface area is greatly increased, and the properties of silica gel desiccant decide to become a good desiccant.Desiccant moisture environment as temperature of the shelf life is most suitable for 20 ~ 32 ℃, humidity was 60% ~ 60%, it can reduce the environmental relative humidity to 40%.

Xinfuda as a China major pharmaceutical packaging manufacturer with DMF, which can offer excellent desiccant packaging for vitamin tablets. Plastic vitamin tube adopted silica-gel desiccant to keep dry and the spring on the cap can prevent tablets damaging.

133mm Vitamin C Tube with Desiccant Cap Y005

133mm effervescent tubes with desiccant closure