Three criteria for effervescent tube selection

 The effervescent tube is a special packaging made of polypropylene in a straight barrel. Today, when the health of the whole people is popularized, we have three more important standard choices when choosing to purchase effervescent tubes, that is:

144mm*29mm effervescent tube packaging

caps for effervescent tube

1. Qualification of effervescent tube manufacturer

In addition to the business qualification requirements of enterprises in China, there are also some requirements for pharmaceutical packaging materials, and it is also necessary to register with the drug supervision and management department and obtain the "Drug Packaging Material Registration Certificate" before production. If the drug needs to be exported to foreign countries, it needs to go through foreign filing, such as EU certification, US DMF filing, etc. And Xinfuda is a company with complete formalities and qualifications.

2. The strength of effervescent tube manufacturers

Manufacturer qualification is the basic requirement for pharmaceutical packaging material manufacturers, followed by strength, such as whether the production equipment is advanced, whether the production process is mature, whether it has a high-standard clean workshop, whether the production scale can meet the needs of pharmaceutical companies, etc. The side reflects the strength of the manufacturer, and a strong manufacturer is more secure in product quality control and post-service.

3. Product quality of effervescent tube

The quality of effervescent tubes is a point that pharmaceutical companies need to pay special attention to. While meeting the requirements of national standards, they must also meet the characteristics of the drug. Cost-effective packaging is the constant pursuit of pharmaceutical companies. On the basis of meeting the above conditions, consider the cost-effectiveness of effervescent tubes.

Of course, when pharmaceutical companies choose effervescent tube suppliers, they generally put product quality and cost-effectiveness first. However, no matter which factor is considered first, the qualification and strength of the manufacturer are still important factors that cannot be ignored.

Three criteria for effervescent tube selection

 The effervescent tube is a special packaging made of polypropylene in a straight barrel. Today, when the health of the whole people is popularized, we have three more important standard choices when choosing to purchase effervescent tubes, that is:

144mm*29mm effervescent tube packaging

caps for effervescent tube

1. Qualification of effervescent tube manufacturer

In addition to the business qualification requirements of enterprises in China, there are also some requirements for pharmaceutical packaging materials, and it is also necessary to register with the drug supervision and management department and obtain the "Drug Packaging Material Registration Certificate" before production. If the drug needs to be exported to foreign countries, it needs to go through foreign filing, such as EU certification, US DMF filing, etc. And Xinfuda is a company with complete formalities and qualifications.

2. The strength of effervescent tube manufacturers

Manufacturer qualification is the basic requirement for pharmaceutical packaging material manufacturers, followed by strength, such as whether the production equipment is advanced, whether the production process is mature, whether it has a high-standard clean workshop, whether the production scale can meet the needs of pharmaceutical companies, etc. The side reflects the strength of the manufacturer, and a strong manufacturer is more secure in product quality control and post-service.

3. Product quality of effervescent tube

The quality of effervescent tubes is a point that pharmaceutical companies need to pay special attention to. While meeting the requirements of national standards, they must also meet the characteristics of the drug. Cost-effective packaging is the constant pursuit of pharmaceutical companies. On the basis of meeting the above conditions, consider the cost-effectiveness of effervescent tubes.

Of course, when pharmaceutical companies choose effervescent tube suppliers, they generally put product quality and cost-effectiveness first. However, no matter which factor is considered first, the qualification and strength of the manufacturer are still important factors that cannot be ignored.

Factors Affecting Moisture Resistance of Effervescent Tablet Tubes

 Effervescent tablet is a new type of preparation, which originated from abroad and has been widely used in China in recent years. Due to the complex and difficult production process and high production cost, this dosage form has very strict requirements on packaging. Then as an effervescent tube as a special packaging for effervescent tablets, in order to prevent the medicine from being damp, denatured, and invalidated, a desiccant is usually placed in the bottle.

144mm*29mm effervescent tube packaging

caps for effervescent tube

But we also need to pay attention to the fact that the desiccant in the effervescent tube is sealed by white cardboard. There are certain requirements for the thickness and moisture content of the cardboard. If the cardboard is too thick, it will enhance the barrier effect on the desiccant and affect its moisture resistance. If the moisture content is too high, the desiccant will apply more moisture absorption performance to the cardboard, reducing the overall moisture resistance of the packaging internal environment. The quality requirements for effervescent tubes are in accordance with the national standard YBB00172004-2015 "Oral Solid Medicinal Low-density Polyethylene Moisture-proof Composite Bottle Caps", in which the requirements for cardboard are as follows: the moisture content is less than 6%, the The lead shall not exceed 0.0005%, and the drug contact surface shall be inspected under the ultraviolet lamp with a wavelength of 365mm and 254mm, and there shall be no flake fluorescence. The thickness is recognized in the industry as 0.46-0.55mm pure high-quality wood pulp white cardboard.

To sum up, the whiteboard must strictly meet the standard requirements, so as to ensure the moisture-proof performance of the desiccant, and then ensure the overall moisture-proof function of the effervescent tablet tube, and protect the health of users.

Effervescent Tablet Tube Test Specification

 The concept of the inspection result exceeding standard management was introduced for the first time, which means that the test result is beyond the legal standard and the enterprise internal control standard. Excessive inspection results do not necessarily mean that the sample inspection is not qualified. How can the effervescent tablet tube manufacturer be implemented?

effervescent packaging

First, the operating procedures for the establishment of inspection results exceeding the limits of the investigation within the company. Laboratory investigation was carried out according to the regulations to confirm whether it was laboratory bias. If it is not the laboratory deviation, the R & D, technology and production personnel should be organized to investigate the production process. It can also be interpreted as two categories: laboratory bias and non laboratory bias.

133*29mm vitamin tablet tube

The laboratory deviation shall investigate any deviation of the test results caused by the factors related to the inspection process,A laboratory survey should be carried out by the professional personnel. The non laboratory deviation refers to the deviation of the test results caused by any other factors except the deviation of the laboratory. The above deviation analysis also standardizes the concrete implementation of the inspection results exceeding the standard for effervescent tablet tube factory. 

What factors should be considered in the packaging design of effervescent tablets

 Effervescent tablets are very common in life, such as vitamin C effervescent tablets are mostly used to enhance human immunity. The effervescent tube is a special packaging for effervescent tablets. To meet the storage requirements of the tablets, the effervescent tube should be designed with full consideration of the characteristics of the dosage form, packaging capacity, and consumer needs.

84mm*29mm effervescent tablet tube

The bottle body and desiccant cap material of effervescent tablets contain a certain amount of moisture. In addition to the penetration of external water molecules during transportation and storage after sealing, the tablets are easily decomposed by moisture, which will cause the medicine to deteriorate. To ensure that the tablet is in a good packaging environment, the effervescent tube should be designed with moisture-proof function as the focus of research.

Effervescent tablets are a kind of ready-to-use solid beverages, and many people carry them with them. Therefore, the effervescent tube should be designed with the capacity of the package in mind. It should be based on the diameter and thickness of the tablet dosage form, combined with the fact that consumers often carry it The characteristics of the bottle determine the capacity of the bottle to better meet the market demand.

On the other hand, due to the characteristics of the dosage form, the hardness of the effervescent tablet should not be too large, and the diameter of the tablet is generally larger, which increases the difficulty of compaction. It is easy to break the effervescent tablet due to collision during logistics and handling. In order to buffer the pressure of the bottle itself and fix the tablets, a soft coil spring is usually placed on the cap of the effervescent tube to absorb shock and avoid shattering.

In fact, no matter how the pharmaceutical packaging is designed, it is inseparable from a fundamental purpose to meet the special properties of drugs and consumer demand. Of course, with the continuous changes in market demand, the effervescent tube will also be upgraded in design.

Viewing the special design of effervescent tube from the importance of medicine moisture prevention

 As a necessary product in our lives, medicine is mainly used to prevent, treat and diagnose various diseases. Because of its direct action on the human body, the safety and effectiveness of medicines are crucial. It is a common choice of many pharmaceutical companies to prevent the deterioration of medicines from moisture absorption through the design of moisture-proof packaging. The common effervescent tube makes good use of this function of packaging.

144mm eff tablet tube

Drugs are prone to deliquescence by absorbing water, especially for effervescent tablets. To achieve the function of moisture-proof, packaging materials are required to have high moisture resistance and low water vapor transmission rate, which can effectively prevent the intrusion of external water vapor and prevent the medicine from being damp.

desiccant cap

In addition, the moisture resistance inside the effervescent tube must also be considered. After the drug is taken, some water vapor may enter the package through the cap during the opening process. Therefore, most of the effervescent tubes are fully considered in the design. When it comes to the importance of moisture-proofing for medicines, a moisture-proof cover is used in the design of the effervescent tube. The moisture-proof cap is a new design that combines the desiccant and the bottle cap into one. There is a small medicine storehouse on the top of the bottle cap to store silica gel and molecular sieve, which can absorb the moisture in the effervescent tube and keep the medicine dry. This design saves space and avoids the risk of children accidentally ingesting the desiccant, and is suitable for test strips and tablet packaging with larger dosage forms.

The special moisture-proof cover design of the effervescent tube is an inevitable trend for pharmaceutical packaging companies to adapt to the changing market needs. We will wait and see what innovative designs for pharmaceutical packaging in the future.