Effervescent tube water vapor transmission rate test

 In the field of pharmaceutical packaging, effervescent tubes play a critical role in protecting moisture-sensitive medications such as vitamin C effervescent tablets, certain tablets, and capsules. Among the various performance indicators, the water vapor transmission rate (WVTR) is a key metric used to assess the moisture barrier properties of effervescent tubes. The accuracy and standardization of WVTR testing methods directly affect the quality and safety of the medications. Let's take a closer look at this crucial testing process.

cap for effervescent tube

I. Significance of Testing: A Critical Line of Defense for Drug Quality

The stability and efficacy of medications are closely tied to their storage conditions, with humidity being one of the most critical factors. As the "protective outerwear" of pharmaceuticals, effervescent tubes must have excellent moisture barrier performance. If the water vapor transmission rate is too high, external moisture can silently seep in and cause the drug to absorb moisture. This not only alters the physical form of the medication—such as causing effervescent tablets to clump or tablets to deform—but can also affect its chemical properties, reducing efficacy and potentially generating harmful impurities that pose health risks to patients. Therefore, accurately testing the WVTR of effervescent tubes is a vital prerequisite for ensuring drug quality and safe, effective medication use.

II. Testing Standards: The Foundation of Standardized Procedures

According to the authoritative Chinese standard "Oral Solid Pharmaceutical Polypropylene Bottles" (YBB00112002-2015), the WVTR testing process for effervescent tubes follows a clearly defined and standardized procedure. Specifically, the test must use Method 3 (2) from "Water Vapor Transmission Rate Testing Method" (YBB00092003-2015). During testing, environmental conditions must be strictly controlled, with temperature maintained at 25°C ± 2°C and relative humidity at 95% ± 5%. Only under these standardized conditions can the resulting WVTR values be accurate and comparable, truly reflecting the moisture barrier performance of the tubes. According to the regulations, the WVTR of effervescent tubes must not exceed 100 mg/24h·L, which serves as a key benchmark for determining whether the tubes meet quality standards.

III. Key Testing Considerations: Ensuring Accuracy and Reliability

In actual testing, many details can impact the accuracy of the results. First, sample selection is crucial. Since factors like material type, thickness, and structure can all affect WVTR, it's essential to select samples with the same material, thickness, and structure. This minimizes errors caused by sample differences and ensures the test accurately reflects the true performance of the effervescent tubes. For example, different materials have different molecular structures and thus vary greatly in their ability to block water vapor; similarly, variations in thickness can influence how easily water vapor penetrates.

effervescent tube

Second, the stability of the testing environment must not be overlooked. Fluctuations in temperature and humidity can affect the diffusion rate of water vapor, thereby skewing test results. In conditions with higher temperatures or unstable humidity, water vapor molecules become more active, potentially increasing the amount that passes through the tube and causing deviations in the results. Thus, testing must be conducted in a stable environment with precisely controlled temperature and humidity. Laboratories must be equipped with high-precision environmental control systems to continuously monitor and adjust conditions, ensuring the entire testing process stays within the required standards.

WVTR testing for effervescent tubes is a vital step in safeguarding the quality and safety of medications. By strictly adhering to testing standards and paying close attention to key details during testing, accurate and reliable results can be obtained, allowing for the selection of high-performance tubes that effectively protect medications during storage and transport—ultimately safeguarding patient health.

Requirements for short-term moisture absorption rate of desiccant for effervescent tubes

 Effervescent tube is a kind of drug storage container with very good moisture-proof performance. The performance of the desiccant directly affects the moisture-proof function of the packaging, so what are the requirements for the short-term moisture absorption rate of the desiccant?

144mm*29mm effervescent tube packaging

The desiccant of the effervescent tube is mostly silica gel, molecular sieve or a mixture of the two in equal proportions. According to the requirements of China YBB00172004-2015 "Quality Standard for Oral Solid Medicinal Low Density Polyethylene Moisture-Proof Combination Caps", the short-term moisture absorption rate of the desiccant is required. as follows:

caps for effervescent tube

In an environment where the relative humidity is less than 60%, take 5 finished bottle caps from the same packaging bag, accurately weigh W0, and put the caps into a constant temperature with a temperature of 25°C±2°C and a relative humidity of 60%±5%. In the constant humidity box, take it out after 1 hour, weigh W1, carefully remove the cardboard, and take out the desiccant that has absorbed moisture: wipe the cardboard and bottle cap clean, and weigh W2 together. Calculated according to the following formula, the short-term moisture absorption rate of silica gel, macromolecular sieve, silica gel: macromolecular sieve (4:6) mixed desiccant shall not exceed 3%, 4.5%, and 3.5%, respectively.

The short-term moisture absorption rate of the desiccant is an important indicator to measure the moisture-proof effect of the packaging in a short time. It is related to whether the moisture-proof function of the packaging can be well exerted, and plays an important role in the stability of the drug during the storage period.

What are the characteristics of the cap of the effervescent tube

 The cap of the effervescent tube is composed of bottle cap skeleton, desiccant, cardboard, and coil spring. It uses the space at the top of the lid to store silica gel and molecular sieve. Silica gel can effectively control the number of water molecules for a long time. Absorbs water molecules, so that the internal moisture can be absorbed and the drug will not get wet.

caps for effervescent tube

Effervescent tablet is a kind of tablet medicine containing disintegrant. It disintegrates instantly when put into water, releasing a large amount of carbon dioxide gas. It has very strict requirements on the moisture-proof performance of the effervescent tube, and its cover not only plays an important role in moisture-proof. It also protects the integrity of the effervescent tablet very well.

144mm*29mm effervescent tube packaging

There is a helical spring on the cap, which is made of soft LDPE material, which can compress the tablet and prevent the drug from breaking due to the impact of various external forces during transportation.

In a word, the cap of the effervescent tube is different from the ordinary bottle cap. It not only isolates the outside world from contact with the inside of the package, but also has the functions of moisture-proof and drug integrity protection. It is a cap with its own characteristics.

Requirements for the moisture content of the desiccant in the effervescent tube

 Effervescent tube is a kind of medicine packaging container with excellent moisture-proof performance. On the one hand, its moisture-proof function is realized through strict sealing. On the other hand, silica gel and molecular sieve desiccant are placed inside the package to absorb the internal moisture.

144mm*29mm effervescent tube packaging

For the moisture content of the two desiccants, effervescent tubes also have relevant regulations. In YBB00172004-2015 "Quality Standard for Oral Solid Pharmaceutical Low Density Polyethylene Moisture-Proof Combination Caps", the requirements for the moisture content of the desiccant are as follows:

caps for effervescent tube

In an environment where the relative humidity of silica gel does not exceed 75%, quickly take out the bottle cap from the closed packaging bag, and take out 5-7g of desiccant from the bottle cap, put it in a weighing bottle (W1) with constant weight, and weigh it. Weight (W2), placed in an oven at 180°C ± 10°C (the total time from opening the bottle cap to the time when the desiccant is placed in the oven should not exceed 5 minutes) to constant weight (weighing as W3), calculated by the following formula, containing water The rate must not exceed 4.8%.

Macromolecular sieve In an environment where the relative humidity does not exceed 75%, quickly take out an appropriate amount of the bottle cap from the closed package, take out the desiccant in the bottle cap with tweezers, and place it in a constant weight crucible W0 (add 8-10g to each crucible). ), accurately weighed W1, placed in a high-temperature furnace at 950°C (the total time from opening the cap packaging bag to placing the desiccant in the high-temperature furnace should not exceed 5 minutes), drying for one hour, taking out the crucible, and accurately weighing after cooling. Determine W2, and calculate according to the following formula, and the moisture content should not exceed 4.8%.

The above are the requirements of the effervescent tube for the moisture content of the desiccant. A qualified desiccant is the basis for ensuring its internal moisture-proof performance and is also an important factor to ensure the stability of the effervescent tablet.

Three main reasons for damp packaging of effervescent tablets

 Effervescent tablet packaging is a straight barreled packaging container, mainly used to store large tablets such as VC effervescent tablets. The main requirement for the packaging of this kind of drugs is moisture-proof. If the tablets are damp, they will easily decompose and deteriorate, which will endanger the safety of patients. If the packaging is found to be damp, the reasons can be analyzed from the following three aspects:

84mm effervescent tablet tube

144mm eff tablet tube supplier

1. Airtightness: If the inside of the effervescent tablet package is damp, first consider whether the airtightness of the package is qualified. The factors that affect the sealing performance mainly depend on the precision of the mold and the strict control of the brother's production process. Packaging materials generally have moisture barrier properties, which can block external water molecules, but if the seal is not tight, it is easy to cause water vapor to enter the package, causing the drug to be damp and deteriorate.

2. Dosage of desiccant: The desiccant inside the drug package is mainly a mixture of silica gel and molecular sieve. If the overall seal is good, the interior of the package still has moisture, it may be because the amount of desiccant is not enough to completely absorb the drug Consider increasing the amount of desiccant due to its own moisture.

3. External environment: The moisture inside the package is also related to the external environment. If the storage environment is too humid, it is easy to get moisture inside the package, so you should try to choose a dry and ventilated place during storage.

On the whole, if the inside of the effervescent tablet package is damp, you can analyze the above three aspects, and after finding the cause, formulate a specific solution to ensure the stability of the drug during storage.

Effervescent Tablet Tube with FDA

 Effervescent tablet tube with FDA as an important packaging for vitamin and chew in effervescent packaging, due to its excellent sealing and desiccant. Xinfuda effervescent tablet tube sizes from 84mm to 144mm with moisture proof tamper closure. The desiccant cap with spring can prevent the tablet shaking.

           

                       

 84mm effervescent tablet tube                                              144mm EFF Tab tube

The cap of effervescent tablet tube takes the important impact on the food or medicine. The tube can be used for vitamin, chew, test strip and so on. Test strip packaging also as a popular packaging in lab test equipment.

                         

spiral desiccant closures                                                       desiccant cap

Effervescent tablet tube is made of PP raw material, which has high hardness, acid and alkali corrosion, high . However its flexibility is lower than PE. Effervescent tablet tube with moisture proof tamper perform well in storing capsules and tablets which need dry condition.

Effervescent Tubes Manufacturer from China

 Effervescent tubes with spiral desiccant closure can be produced by Xinfuda Medical Packaging manufacturer, plastic tube with cap is usually used in effervescent tablet and test strip.

 

 

effervescent tube 

Effervescent tubes with cap are made of different sizes tube and desiccant cap with spiral, which can be more safe for tablets, there are five sizes including 84mm, 99mm, 96mm, 133mm and 144mm. 

Xinfuda Packaging as the best manufacturer in northern China, we have advanced technology and machine to offer healthy and wonderful products for customers.

Introduction of two caps for effervescent tablet packaging

 Effervescent tablet packaging is a packaging containing vitamin effervescent tablets or chewable tablets and other dosage forms. It has good moisture resistance. According to the different packaging requirements of pharmaceutical companies, this packaging contains two types of bottle caps.

caps for effervescent tube

Spring cap: This bottle cap is characterized by a spiral spring on the cap, this spring is made of LDPE raw materials, can play a role in compressing the tablets, and avoid being broken due to various external forces during transportation. It also reduces unnecessary losses for pharmaceutical companies. The LDPE material has good flexibility. The use of this material as a coil spring will neither crush the fragmentation agent due to the too hard texture, nor cause the medicine to be poorly fixed due to the too soft texture and too small pressure. It can give full play to the spring design. The advantages. In addition, this kind of bottle cap also has a feature that it has a desiccant. Unlike ordinary medicine bottles, the effervescent tablet packaging puts the desiccant on the cap, saving space, and is a cap with moisture-proof function. .

effervescent tablet tube 84mm

Non-spring cap: This kind of bottle cap is different from the spring cap. There is no spring on the cap, but it also has a moisture-proof function. Generally, vitamin chewable tablets and small-dose candy tablets will choose this kind of cap, and some vitamin C effervescent tablet manufacturers will also use this kind of bottle cap.

The above are the two types of caps and their characteristics for effervescent tablet packaging. These two different types of caps meet the differentiated needs of pharmaceutical companies for packaging, and are also a manifestation of the continuous development and diversification of pharmaceutical packaging.

Causes and solutions for the brittle body of the effervescent tube

 The quality of medicine packaging directly affects the storage of medicines and even endangers the health of patients. The effervescent tube is a special packaging for large-dose tablets such as effervescent tablets and candy compressed tablets. Sometimes the bottle body may become brittle. What causes this?

144mm*29mm effervescent tablet tube

The effervescent tube is generally processed by injection molding. The bottle body is brittle refers to the cracking or fracture of some parts. It is mainly due to the degradation of the material that causes the macromolecules to break, which reduces the molecular weight of the macromolecules, thereby making the polymer as a whole Physical performance is reduced. It can be solved by the following methods:

In terms of materials, set proper drying conditions before injection molding. If you continue to dry for a few days or the drying temperature is too high, although volatile moisture and other substances can be removed, it is also easy to cause material degradation, especially heat-sensitive plastics. Reduce the use of recycled materials and increase the proportion of virgin materials.

In terms of process conditions, reduce the temperature of the barrel and nozzle, reduce the back pressure, injection pressure, screw speed and injection speed, reduce the generation of excessive shear heat, and avoid polymer decomposition. If it is brittle due to insufficient melt mark strength, the melt mark strength can be increased by increasing the melt temperature and injection pressure. Reduce mold opening speed, ejection speed and ejection pressure.

In addition, to solve the problem of brittleness of the effervescent tube body, it is also necessary to select a suitable screw for the injection molding machine, and the temperature distribution during plasticization is more uniform. If the temperature of the material is uneven, too much heat will easily accumulate locally, leading to degradation of the material.

How is the effervescent tube moisture-proof

 The effervescent tube is a special packaging used to store large-dose medicines such as effervescent tablets and candy tablets. Most of the medicines in this type of tablets contain auxiliary materials such as starch, which are prone to fragments, deliquescent and adhesion after being damp. As a special packaging for these drugs, how can the effervescent tube be moisture-proof?

84mm effervescent tablet tube

The moisture inside the drug packaging mainly comes from two aspects. One is the certain water molecules contained in the tablet itself during the compression process. The other is that in the packaging process, the raw materials will also contain a small amount of water molecules. Generally, in order to maintain the dryness inside the package, a desiccant is placed in the medicine bottle. These desiccants will absorb the moisture inside the package and maintain the stability of the medicine.

144mm*29mm effervescent tube supplier

But the effervescent tube is different from ordinary medicine packaging. Due to the larger dosage form of the tablets and the stacked storage method between the tablets, there is no extra space inside the packaging for the desiccant. After a special design, a small drug warehouse is designed on the cap of the effervescent tube to store silica gel and molecular sieve, which is what we usually call a moisture-proof cap. Such a design can not only absorb internal water vapor and maintain the stability of the drug, but also prevent direct contact between the desiccant and the drug, which is more conducive to the safety of the drug, and to a certain extent, it also avoids the risk of children ingesting the desiccant by mistake.

The effervescent tube guarantees the stability of the medicine with its unique moisture-proof cover. At present, the design of the moisture-proof cover has also been applied to more medicine packaging and played a more important role.

Several factors of damp inside the effervescent tube

 Effervescent tablets are a kind of solid beverage, which will disintegrate quickly when exposed to water. Therefore, the moisture-proof performance of the effervescent tube is stricter. If the inside of the package is damp and the tablet disintegrates, it is mostly related to these factors.

effervescent tablet tube

Moisture-proof is the basic requirement for the pharmaceutical packaging of medicines, especially for some solid medicines. Once the inside of the packaging gets damp, it will easily lead to deterioration or failure of the medicine. If the patient takes the deteriorated medicine by mistake, it will endanger the health of the body. If the inside of the effervescent tube is damp, first consider whether the tightness of the packaging is qualified. The tightness of the effervescent tube mainly depends on the precision of the mold and the control of each production link. Packaging materials generally have moisture barrier properties, which can block the intrusion of external water molecules. However, if the seal is not tight, it is easy to cause water vapor to penetrate into the packaging and make the medicines damp and deteriorate.

On the other hand, also consider the amount of desiccant. The desiccant inside the effervescent tube is mainly a mixture of silica gel and molecular sieve. The drying performance of the desiccant itself is almost the same. If the packaging is well-sealed, the interior of the effervescent tube is still damp, which may be due to dryness. The dosage of the agent is not enough to completely absorb the moisture of the medicine itself, so you can consider increasing the dosage of the desiccant.

In addition, the moisture inside the effervescent tube is also related to the external storage environment. If the external environment is too humid, it is easy to get moisture inside the package. Therefore, when storing the product, choose a dry and ventilated place as much as possible.

The above is the analysis of several main reasons for the internal dampness of the effervescent tube. High-quality packaging is the basic requirement for drug storage. When purchasing effervescent tubes, pharmaceutical companies should pay attention to the product quality while paying attention to the impact of the external storage environment on the drugs.

What factors should be considered in the packaging design of effervescent tablets

 Effervescent tablets are very common in life, such as vitamin C effervescent tablets are mostly used to enhance human immunity. The effervescent tube is a special packaging for effervescent tablets. To meet the storage requirements of the tablets, the effervescent tube should be designed with full consideration of the characteristics of the dosage form, packaging capacity, and consumer needs.

84mm*29mm effervescent tablet tube

The bottle body and desiccant cap material of effervescent tablets contain a certain amount of moisture. In addition to the penetration of external water molecules during transportation and storage after sealing, the tablets are easily decomposed by moisture, which will cause the medicine to deteriorate. To ensure that the tablet is in a good packaging environment, the effervescent tube should be designed with moisture-proof function as the focus of research.

Effervescent tablets are a kind of ready-to-use solid beverages, and many people carry them with them. Therefore, the effervescent tube should be designed with the capacity of the package in mind. It should be based on the diameter and thickness of the tablet dosage form, combined with the fact that consumers often carry it The characteristics of the bottle determine the capacity of the bottle to better meet the market demand.

On the other hand, due to the characteristics of the dosage form, the hardness of the effervescent tablet should not be too large, and the diameter of the tablet is generally larger, which increases the difficulty of compaction. It is easy to break the effervescent tablet due to collision during logistics and handling. In order to buffer the pressure of the bottle itself and fix the tablets, a soft coil spring is usually placed on the cap of the effervescent tube to absorb shock and avoid shattering.

In fact, no matter how the pharmaceutical packaging is designed, it is inseparable from a fundamental purpose to meet the special properties of drugs and consumer demand. Of course, with the continuous changes in market demand, the effervescent tube will also be upgraded in design.

Basic requirements for pharmaceutical packaging

 Pharmaceutical packaging is a container used to store medicines, with different materials and shapes. The main function is to protect medicines in circulation and maintain the safety of medicines within the validity period. The quality of the packaging is related to the efficacy of the medicine and will have a direct impact on the patient's condition. So what should pharmaceutical companies pay attention to when it comes to pharmaceutical packaging?

eye dropper bottle

1. The choice of pharmaceutical packaging should be based on the in-depth knowledge of pharmaceutical companies on medicines. Only by combining the characteristics of medicines to choose the right packaging can better protect the quality of medicines and maintain good efficacy.

2. Make sure that the pharmaceutical packaging complies with the relevant regulations of the national and professional standards.

3. Under normal storage and transportation conditions, medical packaging must ensure that qualified drugs do not deteriorate within the validity period.

effervescent tablet tube

4. Medical packaging (including transportation packaging) must be sealed, sealed, sealed, or used with anti-theft caps, bottle cap sleeves, etc. The label must be affixed and adhered firmly, and must not be put into the bottle together with the drug; any damaged seal, label, packaging container, etc. shall not be shipped or sold.

5. The transport packaging of various drugs must meet the requirements of their physical and chemical properties. All medicines that are afraid of freezing and heat are shipped to different regions in different seasons, and corresponding measures to prevent cold or heat must be taken.

child proof bottle

6. The storage and transportation pictorial signs of drug transport packaging, and the packaging signs of dangerous goods, etc., must comply with national standards and relevant regulations.

Pharmaceutical packaging is nothing trivial. When pharmaceutical companies do a good job in drug research and development, only by choosing qualified and high-quality packaging can they better protect drugs and contribute to human health.

Viewing the special design of effervescent tube from the importance of medicine moisture prevention

 As a necessary product in our lives, medicine is mainly used to prevent, treat and diagnose various diseases. Because of its direct action on the human body, the safety and effectiveness of medicines are crucial. It is a common choice of many pharmaceutical companies to prevent the deterioration of medicines from moisture absorption through the design of moisture-proof packaging. The common effervescent tube makes good use of this function of packaging.

144mm eff tablet tube

Drugs are prone to deliquescence by absorbing water, especially for effervescent tablets. To achieve the function of moisture-proof, packaging materials are required to have high moisture resistance and low water vapor transmission rate, which can effectively prevent the intrusion of external water vapor and prevent the medicine from being damp.

desiccant cap

In addition, the moisture resistance inside the effervescent tube must also be considered. After the drug is taken, some water vapor may enter the package through the cap during the opening process. Therefore, most of the effervescent tubes are fully considered in the design. When it comes to the importance of moisture-proofing for medicines, a moisture-proof cover is used in the design of the effervescent tube. The moisture-proof cap is a new design that combines the desiccant and the bottle cap into one. There is a small medicine storehouse on the top of the bottle cap to store silica gel and molecular sieve, which can absorb the moisture in the effervescent tube and keep the medicine dry. This design saves space and avoids the risk of children accidentally ingesting the desiccant, and is suitable for test strips and tablet packaging with larger dosage forms.

The special moisture-proof cover design of the effervescent tube is an inevitable trend for pharmaceutical packaging companies to adapt to the changing market needs. We will wait and see what innovative designs for pharmaceutical packaging in the future.

Pharmaceutical packaging industry reshuffle

 The General Office of the State Council issued a document requesting to promote the normalization and institutionalization of centralized drug procurement, guide drug prices to return to a reasonable level, and reduce the burden of drug use by the masses. Data shows that as of 2020, the actual procurement volume of centralized drug procurement has reached 2.4 times the agreed procurement volume, and the overall cost savings have exceeded 100 billion yuan.

effervescent tablet tube

Procurement with quantity means that the required quantity of procurement will be announced in the bidding announcement. In the bidding process, in addition to the price, you must also consider whether you can afford the corresponding production energy. In the past, drug bidding only focused on price, not quantity. The winning bidder still needed to work in hospitals to promote the use of medicines; while for volume procurement, the sales of medicines were promised at the same time as the bidding to ensure that they would be used up within a few months. This procurement method can achieve the effect of volume-for-price through market-based bidding among enterprises and reduce the price of drugs purchased.

child proof bottle

For pharmaceutical companies, if the market share is not too high before winning the bid, the shortlisted purchase list can quickly increase sales, and sales will also increase simultaneously, which has the effect of trading price for volume. But if the market share was already high before, the increase in volume may not be enough to make up for the price loss. On the whole, mass procurement has had a huge impact on the entire industry chain of drug research and development, production, circulation, and use. With the continuous deepening and improvement of mass procurement in the pharmaceutical industry, the pharmaceutical market is about to face a major industry reshuffle.

eye dropper bottle

The pharmaceutical industry has started a big wave of sand-washing mode. As a direct contact with drugs, the pharmaceutical packaging industry, which has an important impact on drug quality and drug safety, will also be affected. Good pharmaceutical packaging is critical in meeting regulatory requirements, increasing brand effect, and helping patients comply with medication regulations. Only pharmaceutical packaging can be used as a carrier to enter the circulation market. The market effect of the survival of the fittest in the pharmaceutical industry will inevitably lead to a new round of integration in the pharmaceutical packaging industry, and pharmaceutical packaging material manufacturers without strength will be eliminated.

Will the desiccant in the effervescent tube contaminate the medicine?

 Medicines are items that are kept at home, whether they are medicines or health care products, a large part of them are packaged in plastic pharmaceutica packaging. In order to prevent medicines from getting damp, denatured, and invalidated, a desiccant is generally placed in the bottle. Will the desiccant in the bottle contaminate the medicine? This article will take the effervescent tube packaging as an example to explain in detail.

144mm effervescent ablet tube

First of all, the medicinal desiccant itself is non-toxic and harmless, and has super moisture absorption properties. Before being applied to drugs, it must obtain the "Medicine Packaging Material Registration Certificate" issued by the State Drug Administration. The only desiccant that can be used in medicine is mainly made of silica gel desiccant. This kind of desiccant has stable chemical properties, high adsorption performance, good thermal stability, stable chemical properties, and high mechanical strength. Will cause pollution to medicines.

Secondly, the desiccant placement position of the effervescent tube is special. General drug desiccants are selected in bags and placed together with the drugs. Due to the particularity of effervescent tablets and the space in the bottle, the effervescent tube adopts a desiccant that is more in line with its own storage characteristics. Designed, there is a small medicine storehouse on the top of the bottle cap to store silica gel and molecular sieve. This method can avoid the contact between the desiccant and the medicine, maintain the dryness of the environment in the bottle, and effectively prevent children from eating the desiccant by mistake.

To sum up, unless the packaging of the desiccant in the effervescent tube is damaged, it will cause secondary pollution to the medicine. Under normal circumstances, the medicinal desiccant has less chance of chemical reaction with the common things in life, and the safety is very high.

Desiccant in effervescent tablet packaging

 

Do you know the desiccant in effervescent tablet packaging types? Desiccant is used for medicines, foods are moisture-proof and mildew-proof. Commonly used desiccants can be classified into physical adsorption desiccants and chemical adsorption desiccants. Silica gel desiccants in physical adsorption desiccants meet the US FDA standards and are verified to be free of human body. Silica gel desiccants physically adsorb water molecules in their structures.

The desiccant in the cap of effervescent tubes rarely uses a chemically adsorbed desiccant. Commonly used desiccants for chemical adsorption include quicklime, magnesium chloride, calcium chloride, soda lime, phosphorus pentoxide, etc., absorbing water molecules to change their chemical structure and become another substance. Molecular sieves are another commonly used desiccant. The molecular sieve is a crystalline silicate or aluminosilicate, which is a channel and cavity system formed by a silicon oxytetrahedron or an aluminoxy tetrahedron connected by an oxygen bridge. It can be divided into pore size by high-efficiency desiccant, selective adsorbent, catalyst, ion exchanger, etc. The molecular sieves with pore size less than 2nm, 2-50nm and greater than 50nm are called microporous, mesoporous and macroporous molecular sieves, respectively.