The innovative design of oral liquid bottle cap

 The cap is an important part of the medicinal plastic bottle, which mainly plays the role of sealing. With the continuous changes in market demand, the functionality of the cap is also more diversified. For example, the oral liquid bottle cap adopts an innovative design on the basis of airtightness, so that it has the function of preventing children from opening, reducing the risk of children ingesting medicines by mistake.

 

28mm child resistant  cap for liquid medicine

Oral liquid is a sterile or semi-sterile oral liquid, which is based on traditional Chinese medicine decoction, extracts the active ingredients in the drug, adds flavoring agents, bacteriostatic agents and other additives, and is processed by filling and sealing injection ampoules. Liquid preparations. The packaging of such drugs is generally dominated by plastic bottles or glass bottles, and the lids are mostly ordinary plastic bottle caps. In order to improve the sealing performance, aluminum foil gaskets are used to seal.

Oral liquid tastes better and is easily accepted by patients, especially children. However, children are in the growth and development period and are full of curiosity about many things. It is easy to mistake the oral liquid for a drink, resulting in accidental ingestion. The press-and-screw oral liquid bottle cap adopts an inner and outer double-layer structure. It cannot be opened only by rotating the cap. It must be rotated while pressing down to open. Such an opening method involves the simultaneous application of force in two different directions, which is difficult for children, which can prevent them from easily opening the package in a short period of time and avoid accidental ingestion of medicines.

Rotational medicine caps are not only used in the packaging of liquid preparations, but are also widely used in solid pharmaceutical plastic bottles such as tablets and capsules. The functionality of the lid is well used.

Application of Child Proof Caps-syrup medicine

 In order to prevent children from accidentally opening the packaging and ingesting medicines, many medicines are packaged with a child-resistant opening function. The functions of this type of packaging are mainly realized by the screw-on medicinal bottle caps, which are used in the packaging of children's liquid preparations such as syrup medicine.

100ml PET syrup bottle

28mm child resistant cap

Syrup medicine is a tonic, which has the effect of invigorating Qi and strengthening the spleen, and moderately appetizing. For anorexia caused by spleen and stomach qi deficiency, symptoms include loss of appetite, indigestion, yellow face and thin body, loose stools. In the recipe, Codonopsis, Astragalus, Atractylodes and Chinese yam invigorate Qi and invigorate the spleen; Poria and Coix Seeds are combined with Atractylodes and Chinese yam to enhance the power of invigorating the spleen; Jujube invigorates the middle and invigorates Qi, enhances the efficacy of Codonopsis and Atractylodes; Essence and blood; hawthorn, malt digestion appetizer. All medicines are used together to nourish Qi and strengthen the spleen, and to neutralize the appetizers.

Syrup medicine is a brownish yellow to tan viscous liquid, fragrant and sweet. Preparations with this flavor are easily mistaken for drinks by children, and there is a risk of accidental ingestion of overdose with unimaginable consequences. The screw-on medicinal bottle cap adopts the design of inner and outer double-layer caps, which can be opened by pressing down and rotating at the same time. This opening method is difficult for children to open in a short time, which can effectively prevent them from accidentally eating them.

Not only children's syrup preparations, suspensions, and adult drugs, but also gradually choose this chile prood medicinal bottle cap, which not only protects children's safety, but also reflects the corporate social responsibility, which is conducive to the establishment of a good brand image.

Three kinds of bottle caps for moisture-proof packaging

 The bottle cap is an important part of pharmaceutical packaging. Its basic function is to seal. With the continuous evolution of packaging functions and forms, the types of caps are also changing. There are three main types of bottle caps commonly used in moisture-proof packaging of medicines.

child resistant cap

medicine cap

desiccant cap

1. Common cap: refers to the common screw cover, which is also a common cover in our life. The moisture-proof packaging of medicines that choose this kind of cap is generally sealed with an aluminum foil gasket to enhance the overall sealing of the bottle.

2. Moisture-proof cover: Most of the moisture-proof medicine packaging adopts the method of built-in desiccant, and the desiccant is placed directly with the medicine in a bag. The moisture-proof cap utilizes the space at the top of the bottle cap and puts the desiccant in the small medicine compartment on the top of the cap. This not only avoids the direct contact between the medicine and the desiccant, but also prevents children from accidentally eating the desiccant.

3. Chind resistant cap: This kind of cap is mainly to prevent children from opening the package at will and eating medicines by mistake. It is composed of an inner and outer double-layer structure. If the lid needs to be pressed down and rotated at the same time, this opening method is difficult for children and can play a good anti-opening function. For adults, it can be easily opened according to the prompts.

On the whole, the caps of the moisture-proof packaging of medicines mainly include ordinary lids, moisture-proof lids, and pressure-screw lids. There are also some packages that use moisture-proof pressure-screw lids. The lids are both moisture-proof and child-proof.

Pharmaceutical high-density polyethylene bottles need to meet these characteristics

 As a common polymer material, high-density polyethylene is often processed into high-density polyethylene bottles, which are used in all aspects of our daily life, such as shampoo, hand sanitizer, detergent, beverage bottles, etc., among which pharmaceutical packaging It is also one of its applications.

child proof bottle

Medicine is a special item, and its quality is related to the health of patients. Therefore, high-density polyethylene bottles also need to be strictly controlled to meet safety requirements in quality. Safety mainly depends on packaging materials. High-density polyethylene is one of the common materials for pharmaceutical packaging. It is non-toxic, tasteless, resistant to most acids and alkalis, light in weight, and easy to transport. This material has been included in the national pharmaceutical packaging materials. And the container registration certificate quality standard, its detection method, experiment, sterility, easy oxidizing, etc. have clear regulations, which can ensure the safety and stability of the drug.

In addition, the high-density polyethylene bottle should also consider the convenience of patients, which needs to be considered from the design of its appearance. At present, the shapes of medicine bottles include square, oval, round, etc. Among them, round high-density polyethylene bottles are more commonly used than other shapes. This is mainly because the circular design is not only in line with people’s aesthetics. It also caters to the principles of human mechanics and meets the needs of patients for easy grasping.

Hygiene, safety and convenient use are the two basic requirements of medicinal high-density polyethylene bottles. They seem to be simple. Behind it requires manufacturers of pharmaceutical packaging materials to repeatedly modify the appearance design, strictly control product quality management, and constantly pursue higher quality. Medicine packaging.

Prevent children from opening bottles to help pharmaceutical companies break through

 Recently, the State Food and Drug Administration passed the priority review and approval procedure and conditionally approved the listing of the Class 1 innovative drug vometinib mesylate (trade name: Ivesa) declared by Shanghai Ailisi Pharmaceutical Technology Co., Ltd., which is also The second domestically produced Class 1 new chemical drug approved for marketing this year.

The drug is the third representative EGFR kinase inhibitor, and is an innovative drug independently researched and developed by my country with independent intellectual property rights. Applicable to the disease progression during or after treatment with previous epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), and the presence of locally advanced or metastatic non-small cell lung cancer with positive EGFR T790M mutation confirmed by testing ( NSCLC) treatment of adult patients.

The launch of this drug will bring new choices for lung cancer patients, and competition in the lung cancer drug market will also become more intense. Innovation is the foundation of enterprise development. Pharmaceutical companies must continue to innovate and develop new drugs that meet market needs if they want to survive in the ever-changing market. In addition, pharmaceutical packaging also needs continuous innovation. At present, some anti-cancer drugs, high blood pressure and other drugs mostly use the special packaging method of preventing children from opening the bottle, in order to find a breakthrough in the fierce market competition.

child proof bottle

The main function of the child-proof bottle is to prevent children from opening the pharmaceutical packaging and accidentally ingesting drugs. The United States has implemented the Poison Prevention Packaging Act (PPPA) as early as 1970, requiring certain products that are potentially threatening to children to use child-proof packaging. More and more developed countries are implementing it. With the continuous innovation of medicines and people's attention to the problem of children's accidental ingestion of medicines, child-proof bottles will be applied to more medicine packaging, to a certain extent, to help companies establish a good brand image and improve product competitiveness.

How to test the safety of child-proof bottles

 With the development of the pharmaceutical industry, a variety of new preparations emerge in an endless stream, and the safety of pharmaceutical packaging has also received more and more attention. Among them, whether children can effectively prevent children from opening the packaging and accidentally eating drugs has become a problem that pharmaceutical companies need to consider. The emergence of the open bottle successfully solved this problem.

45ml plastic medicine bottle with crc

The child-proof bottle is a special packaging with protective function. Its characteristics are mainly reflected in the bottle cap. The bottle cap is composed of an inner and outer double layer structure and is connected by a card slot. Only rotating the outer cap cannot open the package. It needs to be downwards. The bottle cap can be opened by rotating the bottle while pressing. The child is still in the developmental stage and has poor physical coordination. It is difficult to open the package, which effectively reduces the risk of accidental eating.

The child-proof packaging regulations are aimed at children younger than 5 years old, so how to test the safety of child-proof bottles? The United States Code of Federal Regulations requires that 50 children be divided into three age groups and asked to open the child-proof packaging to be tested. The test time is 10 minutes. If a child fails to open the package within the first 5 minutes, then the package will receive a certificate and the test will continue for 5 minutes. If a child opens the package within the first 5 minutes or within the next 5 minutes, then the package fails the child. To pass the test, no less than 85% of children must be unable to open the package in the first 5 minutes, and no less than 80% of children cannot open the package in the next 5 minutes. If the results of multiple tests are inconsistent, you need to change to another wave, and the number of children to be tested should not exceed 200.

Child safety is a matter of great concern to the country and every family. The use of child-proof bottles for medicines is an effective measure to reduce the accidental consumption of medicines by children, and it is also the joint responsibility of pharmaceutical companies and pharmaceutical packaging companies.

How to test the safety of child-proof bottles

 With the development of the pharmaceutical industry, a variety of new preparations emerge in an endless stream, and the safety of pharmaceutical packaging has also received more and more attention. Among them, whether children can effectively prevent children from opening the packaging and accidentally eating drugs has become a problem that pharmaceutical companies need to consider. The emergence of the open bottle successfully solved this problem.

45ml plastic medicine bottle with crc

The child-proof bottle is a special packaging with protective function. Its characteristics are mainly reflected in the bottle cap. The bottle cap is composed of an inner and outer double layer structure and is connected by a card slot. Only rotating the outer cap cannot open the package. It needs to be downwards. The bottle cap can be opened by rotating the bottle while pressing. The child is still in the developmental stage and has poor physical coordination. It is difficult to open the package, which effectively reduces the risk of accidental eating.

The child-proof packaging regulations are aimed at children younger than 5 years old, so how to test the safety of child-proof bottles? The United States Code of Federal Regulations requires that 50 children be divided into three age groups and asked to open the child-proof packaging to be tested. The test time is 10 minutes. If a child fails to open the package within the first 5 minutes, then the package will receive a certificate and the test will continue for 5 minutes. If a child opens the package within the first 5 minutes or within the next 5 minutes, then the package fails the child. To pass the test, no less than 85% of children must be unable to open the package in the first 5 minutes, and no less than 80% of children cannot open the package in the next 5 minutes. If the results of multiple tests are inconsistent, you need to change to another wave, and the number of children to be tested should not exceed 200.

Child safety is a matter of great concern to the country and every family. The use of child-proof bottles for medicines is an effective measure to reduce the accidental consumption of medicines by children, and it is also the joint responsibility of pharmaceutical companies and pharmaceutical packaging companies.

How to test the safety of child-proof bottles

 With the development of the pharmaceutical industry, a variety of new preparations emerge in an endless stream, and the safety of pharmaceutical packaging has also received more and more attention. Among them, whether children can effectively prevent children from opening the packaging and accidentally eating drugs has become a problem that pharmaceutical companies need to consider. The emergence of the open bottle successfully solved this problem.

45ml plastic medicine bottle with crc

The child-proof bottle is a special packaging with protective function. Its characteristics are mainly reflected in the bottle cap. The bottle cap is composed of an inner and outer double layer structure and is connected by a card slot. Only rotating the outer cap cannot open the package. It needs to be downwards. The bottle cap can be opened by rotating the bottle while pressing. The child is still in the developmental stage and has poor physical coordination. It is difficult to open the package, which effectively reduces the risk of accidental eating.

The child-proof packaging regulations are aimed at children younger than 5 years old, so how to test the safety of child-proof bottles? The United States Code of Federal Regulations requires that 50 children be divided into three age groups and asked to open the child-proof packaging to be tested. The test time is 10 minutes. If a child fails to open the package within the first 5 minutes, then the package will receive a certificate and the test will continue for 5 minutes. If a child opens the package within the first 5 minutes or within the next 5 minutes, then the package fails the child. To pass the test, no less than 85% of children must be unable to open the package in the first 5 minutes, and no less than 80% of children cannot open the package in the next 5 minutes. If the results of multiple tests are inconsistent, you need to change to another wave, and the number of children to be tested should not exceed 200.

Child safety is a matter of great concern to the country and every family. The use of child-proof bottles for medicines is an effective measure to reduce the accidental consumption of medicines by children, and it is also the joint responsibility of pharmaceutical companies and pharmaceutical packaging companies.

Basic requirements for pharmaceutical packaging

 Pharmaceutical packaging is a container used to store medicines, with different materials and shapes. The main function is to protect medicines in circulation and maintain the safety of medicines within the validity period. The quality of the packaging is related to the efficacy of the medicine and will have a direct impact on the patient's condition. So what should pharmaceutical companies pay attention to when it comes to pharmaceutical packaging?

eye dropper bottle

1. The choice of pharmaceutical packaging should be based on the in-depth knowledge of pharmaceutical companies on medicines. Only by combining the characteristics of medicines to choose the right packaging can better protect the quality of medicines and maintain good efficacy.

2. Make sure that the pharmaceutical packaging complies with the relevant regulations of the national and professional standards.

3. Under normal storage and transportation conditions, medical packaging must ensure that qualified drugs do not deteriorate within the validity period.

effervescent tablet tube

4. Medical packaging (including transportation packaging) must be sealed, sealed, sealed, or used with anti-theft caps, bottle cap sleeves, etc. The label must be affixed and adhered firmly, and must not be put into the bottle together with the drug; any damaged seal, label, packaging container, etc. shall not be shipped or sold.

5. The transport packaging of various drugs must meet the requirements of their physical and chemical properties. All medicines that are afraid of freezing and heat are shipped to different regions in different seasons, and corresponding measures to prevent cold or heat must be taken.

child proof bottle

6. The storage and transportation pictorial signs of drug transport packaging, and the packaging signs of dangerous goods, etc., must comply with national standards and relevant regulations.

Pharmaceutical packaging is nothing trivial. When pharmaceutical companies do a good job in drug research and development, only by choosing qualified and high-quality packaging can they better protect drugs and contribute to human health.

Child proof containers wholesale

Childproof Caps that Keep Products and Kids Safe

Need a cap that protects young ones from easily accessing harmful contents in a container? These Child Resistant Caps (CRC) that can be used on either plastic or metal containers.Child resistant closures for metal containers are usually lined with a type of foil or liner that is compatible with metal containers. Cap styles are available as Pictorial, PDT or "Push Down & Turn", Chem Lock (outer protective tab), and Stolz (made for tin-plate containers with a senior-friendly design for REL openings). 

child proof container wholesale

Plastic caps for sealing, dispensing, spraying, pumping or misting. Our caps come with a variety of liner options including pressure sensitive, heat induction, foam and more. Plastic cap styles include continuous thread plastic caps, child resistant caps, tamper evident caps, dispensing caps, lotion pumps, mist sprayers and trigger sprayers. Metal caps include standard caps, brush caps, child resistant caps, dauber caps, and inner seals.

plastic cap details

Why Pharma Factories Choose Child Resistant Cap

Pharma bottle with child resistant cap is that preventing children opening the pharma bottle package. So why we must choose this package for medicine?

From the view of pharmacology and toxicology, children are immature due to the body’s development, some drugs are not suitable for children due to drugs’ particularity and complexity when metabolisming in vivo. However there are some colorful, shaping and sweet icing tempting children of tender years. Children open the bottle and eat by mistanke will cause some damage and maybe sequelae. There will reduce the damage if use the child resistant cap bottle.

 

child resistant cap bottle

The number of left-behind children in China reached 58 million five years ago, with more than 40 million left-behind children under the age of 14, now a larger proportion. More than 80 percent of the left-behind children are separated by grandparents and temporary guardianship of relatives and friends.The responsibility of guardianship is not carried out and the guard is not aware. The left-behind children are more vulnerable to accidental injury.

60ML bottle with push and turn cap 

The technology and industry of China's production and use of child safety protection devices are very mature. The usage of child resistant cap bottle will also reduce the occurrence of drug incident in children.