Introduction of two caps for effervescent tablet packaging

 Effervescent tablet packaging is a packaging containing vitamin effervescent tablets or chewable tablets and other dosage forms. It has good moisture resistance. According to the different packaging requirements of pharmaceutical companies, this packaging contains two types of bottle caps.

caps for effervescent tube

Spring cap: This bottle cap is characterized by a spiral spring on the cap, this spring is made of LDPE raw materials, can play a role in compressing the tablets, and avoid being broken due to various external forces during transportation. It also reduces unnecessary losses for pharmaceutical companies. The LDPE material has good flexibility. The use of this material as a coil spring will neither crush the fragmentation agent due to the too hard texture, nor cause the medicine to be poorly fixed due to the too soft texture and too small pressure. It can give full play to the spring design. The advantages. In addition, this kind of bottle cap also has a feature that it has a desiccant. Unlike ordinary medicine bottles, the effervescent tablet packaging puts the desiccant on the cap, saving space, and is a cap with moisture-proof function. .

effervescent tablet tube 84mm

Non-spring cap: This kind of bottle cap is different from the spring cap. There is no spring on the cap, but it also has a moisture-proof function. Generally, vitamin chewable tablets and small-dose candy tablets will choose this kind of cap, and some vitamin C effervescent tablet manufacturers will also use this kind of bottle cap.

The above are the two types of caps and their characteristics for effervescent tablet packaging. These two different types of caps meet the differentiated needs of pharmaceutical companies for packaging, and are also a manifestation of the continuous development and diversification of pharmaceutical packaging.

The structure and function of the effervescent tube cap

 The advantages and disadvantages of the pharmaceutical packaging and the functional design are very important for the storage of medicines. The effervescent tube is a special type of medicine packaging. Its bottle cap is composed of a desiccant, a coil spring and an anti-theft ring. Each design is large. useful.

sprial cap

Desiccant: In order to prevent the medicine from absorbing moisture and deteriorating, a desiccant is placed inside the medicine packaging. Commonly used desiccants include quicklime, magnesium chloride, calcium chloride, phosphorus pentoxide, molecular sieves, etc. Unlike other packaging, the desiccant of the effervescent tube is placed in the small medicine bin on the top of the bottle cap. This design reduces the contact between the desiccant and the medicine, and also reduces the risk of children ingesting the desiccant by mistake.

Coil spring: The effervescent tablet has a large dosage form and is easily damaged by various external forces during transportation. The spiral spring on the bottle cap is soft and can compress the tablets to prevent the effervescent tablet from breaking during transportation and handling, and it protects the integrity of the medicine.

Anti-theft ring: The design of the anti-theft ring on the cap of the effervescent tube is derived from the beverage bottle. When the cap is unscrewed, the anti-theft ring will fall off and stay on the bottle. We can judge whether the medicine has been opened according to the state of the anti-theft ring.

The special design of the effervescent tube cap is the result of the ever-changing market demand, and it is also the embodiment of the packaging manufacturer's continuous innovation and innovation in the production process. With the increase of various kinds of medicines, there will be more and more new medicines, and the design of medicine packaging will also show a diversified development trend.

How Can Plastic Vitamin Tube Keep Dry Environment

 Plastic vitamin tube is used in vitamin tablet packaging due to its dry environment. There are silical-gel desiccant and large molecular sieve desiccant in plastic vatimin tube. However, silica-gel desiccant is the only one through FDA and healthy for human.

 

spiral desiccant closure

 

Silica-gel desiccant in vitamin tube is a highly active adsorbent material, which belongs to amorphous material. Silic-gel desiccant of vitamin tube cap insoluble in water, non-toxic and tasteless, chemically stable. According to diameter, silica can be divided into macroporous silica gel, coarse - hole silica gel, type B silicone, fine - hole silica gel. Silica can reuse through rebirth. The main ingredient of silica-gel desiccant is Sio2, for more translucent amorphous, composed of natural mineral processed granular or bead, usually after treatment with sulfuric acid to form, its hard, non-toxic, tasteless, non-corrosive, good chemical stability and thermal stability.

plastic vitamin C tube

 

Silica-gel desiccant of vitamin tube covers many hydroxyl groups with strong hydrophilicity, at the same time, the surface of silica gel desiccant has many small holes that are not visible to the naked eye, so that its surface area is greatly increased, and the properties of silica gel desiccant decide to become a good desiccant.Desiccant moisture environment as temperature of the shelf life is most suitable for 20 ~ 32 ℃, humidity was 60% ~ 60%, it can reduce the environmental relative humidity to 40%.

Xinfuda as a China major pharmaceutical packaging manufacturer with DMF, which can offer excellent desiccant packaging for vitamin tablets. Plastic vitamin tube adopted silica-gel desiccant to keep dry and the spring on the cap can prevent tablets damaging.

Viewing the special design of effervescent tube from the importance of medicine moisture prevention

 As a necessary product in our lives, medicine is mainly used to prevent, treat and diagnose various diseases. Because of its direct action on the human body, the safety and effectiveness of medicines are crucial. It is a common choice of many pharmaceutical companies to prevent the deterioration of medicines from moisture absorption through the design of moisture-proof packaging. The common effervescent tube makes good use of this function of packaging.

144mm eff tablet tube

Drugs are prone to deliquescence by absorbing water, especially for effervescent tablets. To achieve the function of moisture-proof, packaging materials are required to have high moisture resistance and low water vapor transmission rate, which can effectively prevent the intrusion of external water vapor and prevent the medicine from being damp.

desiccant cap

In addition, the moisture resistance inside the effervescent tube must also be considered. After the drug is taken, some water vapor may enter the package through the cap during the opening process. Therefore, most of the effervescent tubes are fully considered in the design. When it comes to the importance of moisture-proofing for medicines, a moisture-proof cover is used in the design of the effervescent tube. The moisture-proof cap is a new design that combines the desiccant and the bottle cap into one. There is a small medicine storehouse on the top of the bottle cap to store silica gel and molecular sieve, which can absorb the moisture in the effervescent tube and keep the medicine dry. This design saves space and avoids the risk of children accidentally ingesting the desiccant, and is suitable for test strips and tablet packaging with larger dosage forms.

The special moisture-proof cover design of the effervescent tube is an inevitable trend for pharmaceutical packaging companies to adapt to the changing market needs. We will wait and see what innovative designs for pharmaceutical packaging in the future.

Viewing the special design of effervescent tube from the importance of medicine moisture prevention

 As a necessary product in our lives, medicine is mainly used to prevent, treat and diagnose various diseases. Because of its direct action on the human body, the safety and effectiveness of medicines are crucial. It is a common choice of many pharmaceutical companies to prevent the deterioration of medicines from moisture absorption through the design of moisture-proof packaging. The common effervescent tube makes good use of this function of packaging.

144mm eff tablet tube

Drugs are prone to deliquescence by absorbing water, especially for effervescent tablets. To achieve the function of moisture-proof, packaging materials are required to have high moisture resistance and low water vapor transmission rate, which can effectively prevent the intrusion of external water vapor and prevent the medicine from being damp.

desiccant cap

In addition, the moisture resistance inside the effervescent tube must also be considered. After the drug is taken, some water vapor may enter the package through the cap during the opening process. Therefore, most of the effervescent tubes are fully considered in the design. When it comes to the importance of moisture-proofing for medicines, a moisture-proof cover is used in the design of the effervescent tube. The moisture-proof cap is a new design that combines the desiccant and the bottle cap into one. There is a small medicine storehouse on the top of the bottle cap to store silica gel and molecular sieve, which can absorb the moisture in the effervescent tube and keep the medicine dry. This design saves space and avoids the risk of children accidentally ingesting the desiccant, and is suitable for test strips and tablet packaging with larger dosage forms.

The special moisture-proof cover design of the effervescent tube is an inevitable trend for pharmaceutical packaging companies to adapt to the changing market needs. We will wait and see what innovative designs for pharmaceutical packaging in the future.

Test standard of desiccant cap

 

desiccant caps for pharma bottles

The following is the test standard for pharmaceutical desiccant caps:

1. Appearance

According to the quality requirements of plastic products, combined with the actual sample description, in line with the purpose of fully reflecting the quality of the product.

2. Identification

In order to effectively control the quality of the product and strengthen the monitoring of the formula and set the project, we refer to the YBB00172004-2015 method, select the infrared spectrum and density test, the index is consistent with YBB00112002-2015

3. Residue on ignition

The purpose of this test is to control the inorganic impurities in the plastic. We followed the 0.1% standard for YBB00172004-2015 and the 3.0% standard for the cover with sunscreen.

4. Desiccant Moisture Content Desiccant is a highly absorbent material that may absorb water during production. In order to ensure the quality of the product, it is necessary to control the moisture content of the desiccant to ensure the quality of the product before use.

5. Saturating agent saturated moisture absorption rate 

The desiccant capacity of the desiccant is an important indicator to check the quality of the desiccant. The saturated moisture absorption rate of different desiccants is different. To achieve the saturation of moisture absorption, it is taken out to constant weight after 8 days.

6. Short-term moisture absorption rate of desiccant

The short-term moisture absorption capacity of desiccant is also an important indicator to examine the quality of desiccant, simulating the hygroscopicity of the product during use.

7. Drop resistance

This product is a combination and should consider the combined performance of the product.

8. Physical and chemical properties of cardboard

According to the requirements of YBB00172004-2015, the physical and chemical indicators of cardboard have been established.

9. Dissolution test

Easy Oxide This item is designed to control the impurities in the water-soluble extract of the product that may affect the safety and effectiveness of the drug. Method YBB00172004-2015, the indicator is still no more than 1.0ml.

Heavy metals To control the total amount of heavy metals, set this item. . The method of the Pharmacopoeia of the People's Republic of China is adopted, and the indicator is one in a million

Non-volatile methods and indicators are fully based on the requirements of YBB00172004-2015.

10. Microbiological limits The method of the Pharmacopoeia of the People's Republic of China shall be adopted and shall comply with the regulations.

11. Abnormal toxicity The method of the Pharmacopoeia of the People's Republic of China is adopted and should comply with the regulations.

Test standard of desiccant cap

 

desiccant caps for pharma bottles

The following is the test standard for pharmaceutical desiccant caps:

1. Appearance

According to the quality requirements of plastic products, combined with the actual sample description, in line with the purpose of fully reflecting the quality of the product.

2. Identification

In order to effectively control the quality of the product and strengthen the monitoring of the formula and set the project, we refer to the YBB00172004-2015 method, select the infrared spectrum and density test, the index is consistent with YBB00112002-2015

3. Residue on ignition

The purpose of this test is to control the inorganic impurities in the plastic. We followed the 0.1% standard for YBB00172004-2015 and the 3.0% standard for the cover with sunscreen.

4. Desiccant Moisture Content Desiccant is a highly absorbent material that may absorb water during production. In order to ensure the quality of the product, it is necessary to control the moisture content of the desiccant to ensure the quality of the product before use.

5. Saturating agent saturated moisture absorption rate 

The desiccant capacity of the desiccant is an important indicator to check the quality of the desiccant. The saturated moisture absorption rate of different desiccants is different. To achieve the saturation of moisture absorption, it is taken out to constant weight after 8 days.

6. Short-term moisture absorption rate of desiccant

The short-term moisture absorption capacity of desiccant is also an important indicator to examine the quality of desiccant, simulating the hygroscopicity of the product during use.

7. Drop resistance

This product is a combination and should consider the combined performance of the product.

8. Physical and chemical properties of cardboard

According to the requirements of YBB00172004-2015, the physical and chemical indicators of cardboard have been established.

9. Dissolution test

Easy Oxide This item is designed to control the impurities in the water-soluble extract of the product that may affect the safety and effectiveness of the drug. Method YBB00172004-2015, the indicator is still no more than 1.0ml.

Heavy metals To control the total amount of heavy metals, set this item. . The method of the Pharmacopoeia of the People's Republic of China is adopted, and the indicator is one in a million

Non-volatile methods and indicators are fully based on the requirements of YBB00172004-2015.

10. Microbiological limits The method of the Pharmacopoeia of the People's Republic of China shall be adopted and shall comply with the regulations.

11. Abnormal toxicity The method of the Pharmacopoeia of the People's Republic of China is adopted and should comply with the regulations.

What is role for silica gel in desiccant packaging？

Silica gel desiccant packaging is commonly used to control the moisture and humidity, and to adsorb HC1, CO2, C12 or aromatic. Desiccant is basically made from silicon dioxide that works efficiently in protecting the food products and pharmaceutical tablets and capsules from moisture inside the packaging tube, bottle or container. Whether you use silica gel in food and medicine, they are harmless and are highly suitable to remove the relative humidity from the packaging environment. To get rid of moisture that may harm your products, you must use the perfect silica gel packets containing white, blue or orange beads based on their level of adsorption capacity.

desiccant caps

Silica gel is a non-corrosive and non-toxic way of controlling the moisture. They are available in varying volumes and can be obtained in bulk quantities. They are used in variety of applications such as medications, diagnostic kits, dried and freeze goods packaging, food packaging, pharmaceutical packaging and many more.These desiccants can also be used in high frequency radio and satellite transmission system where high quality moisture adsorbents are required to prevent the signal degradation.

packaging for effervescent tablets

 Such type of desiccants provides maximum adsorption capacity and prevents the products from mold, mildew, rust or corrosion by filling the packets with non-indicating silica gel desiccant.

Contact us

email: pharma-pack@fudaplastic.com

tell: +86 15731938681

Classification of pharma caps

The pharma caps are made of plastic materials and are integrated into a multi-functional cap. There are many product categories. According to the needs of pharmaceutical companies, there are mainly the following:

desiccant caps

1) Tamper proof cap also known as anti-theft cover; anti-movement logo is also called anti-motion ring, safety ring. It is based on the common threaded cover, adding a circle of skirt around the bottom of the cover, and connecting with multiple points. When twisting the bottle cap, the corrugated teeth are fastened to the hoop on the lower end of the bottle mouth. When the bottle is reversed, the skirt lock ring is detached. For the first time, the bottled drug is first checked to see if the lid lock ring is intact. It can be judged whether the plastic bottle has been opened and whether the drug has been tampered with or stolen. The torque force that opens the cover to allow the skirt to fall off smoothly should be mild and modest.

2) The moisture-proof cover is a kind of packaging form that integrates the moisture-proof agent into the bottle cap, which can reduce the intrusion of moisture during use. Currently, the moisture-proof bottle is widely used.

3) Anti-sloshing caps, a form of packaging that integrates the cushioning body into the base of the cap to prevent damage such as capsules from being shaken.

4) Booster cover, a form of packaging to increase the opening of the assist mechanism

5) Trademark cover Integrate the trademark with the bottle cap

6) Quantitative cover for integrated quantitative change

7) Sealing system, the integrated system is integrated so that the bottle itself must not be reused after one use.

Moisture proof vials feature

The moisture proof vials have a double-layer structure of two layers inside and outside, the inner side of the top of the outer cover and the outer side of the top of the inner cover are connected by a card slot, and has an anti-child opening function, there is a medicine warehouse at the top of the inner cover, the medicine There is a partition in the middle of the silo, and the desiccant is placed in the silo. The top of the silo is connected with the inner ring of the inner lid, and the medicine silo is a vent hole of the medicine silo, and the inner plug is provided at the top of the inner lid. The tight fit between the inner stopper and the bottle mouth ensures the tightness of the bottle. The outer cover has a safety ring. When the cover is tightened, the safety teeth on the safety ring and the bottle safety teeth will interact with each other. The safety teeth of the bottle on the safety ring will interact, and the safety ring and the cover will be separated. This process cannot be repeated.

effervescent packaging

effervescent tablet tubes with desiccant cap

Moisture proof vials produced in HDPE by injection blow molding for superior quality and dimensional accuracy, the feature of desiccant bottle as following:

Tamper-evident screw-on caps, with or without silica desiccant capsules; Range of liners and seals according to type of application.

moisture proof bottle

The moisture proof vial is equipped with a small drug storage bag containing a moisture-proofing agent and an anti-oxidant. The medicine bottle cannot be opened by the child after the first opening, thereby making the spirit and heart having the danger of preventing the child from eating the enabled teammate. Cerebrovascular drugs and contraceptives; and the anti-moisture agent and anti-oxidant in the small drug can reduce the moisture absorption and oxidation process of the activated drugs during the effect period to maintain the safety of the drug.

plastic tubes for candy with lids

Novelty and design packaging is popular in the market. Today, let's talk about pills and tablets packaging, like pills candy. all andy need a dry environment to keep the sahpe. In the past, all candy usually in clear jar with different colors.

plastic tube for candy

Xinfuda designs a new plastic tube for tablets, now we have plastic tube 48mm, 63mm, 99mm with lids, 84mm, 96mm,133mm, 144mm with spiral desiccant cap,  all plastic tube with cap with desiccant, so all can be in a dry environment.

plastic tube with lids

Chewing gum tube, plastic candy jar and effervescent tablet tubes are all use Xinfuda plastic tube. Plastic tubes for candy is consist of empty tube and desiccant cap, there are gel silica in the cap to absorb moisture.

desiccant cap