2021年4月29日星期四

The packaging ignores this, the effect of pet nutrition cream is halved

 As a health care product, pet nutrition cream has a significant effect on weak, elderly dogs and cats, dogs and cats recovering their physical fitness after surgery and illness, and pets who need to improve immunity. At present, pet nutrition cream has adopted a new type of pre-filled packaging. To ensure the maximum effect of the nutrition cream, the tightness of the package is very important.

The packaging ignores this, the effect of pet nutrition cream is halved

15ml dosing syringe for pets

Tightness is an important indicator of veterinary packaging quality, related to the product quality and expiration date of the packaging contents, and is also a necessary guarantee for the product circulation environment. As a new type of drug packaging method, prefilling has the characteristics of convenient use and simple operation. Generally speaking, its tightness is mainly controlled by the following points:

First, the sealing member. The use of sealing components that comply with internationally accepted standards is the basis for ensuring the tightness of the package;

Second, the necessary verification. When the components of the sealing system or the potting system are changed, the impact on the sealing system should be evaluated in time, and the sealing integrity should be verified again when necessary;

Third, meet the test requirements. The verification of tightness requirements shall meet the requirements of bacteria intrusion test and saturated salt water test;

Fourth, other experimental evidence. In addition to the conventional experimental methods for prefilled syringes, influencing factor experiments and accelerated experiments should also be carried out to ensure that its sealing performance during the validity period meets user requirements.

The airtightness of the veterinary syringe is of great significance to the efficacy of pet nutrition cream. If the airtightness of the packaging is not good, it will have a certain impact on the brand image of the pharmaceutical company. Therefore, when choosing a packaging manufacturer, the pharmaceutical company should do the packaging performance Comprehensive assessment.

2021年4月28日星期三

FDA and pets food packaging requirement

 At FDA,the safety of food for animal, including our pets,is just as important as the safety of food for people. In fact,Congress directed FDA to protect"articles used for food or drink for man or other animals." Under this lae, we are determined to make sure the food and treats we give our dogs and cats, of course, but also companion animals like horse, hamsters, birds, and fish, is safe for the animal to eat.

According to law, companies producing canned pet food must follow a specific set of regulations to eliminate harmful becteria inside the can. These are the same regulations that manufacturers of canned foods for people must follow. Pets food and treats must also be truthfully labeled, and federal regulations require labels on pet foods and treats to have four specific pieces of information.

Number one: The label must contain a list of the ingredients.
INGREDIENTS: Wheat Flour Wheat Bran, Meat and Bone Meai Milk, Wheat Germ, Beef Fat (Preserved withtocopherols), Dicalcium Phosphate, Caramel Color, Salt, Natural Flavor, Artificial Beef Flavor,
Vitamins and Minerals(Choline Chloride, Zinc Sulfate, Vitamin E Supplement L-ascorbyl-2-polyphosphate Biotin, Ferrous Sulfate, D-calcium, Niacin Supplement, Riboflavin Supplement, Vitamin B12 Supplement, Ferrous Sulfate, D-calcium Pantothenate, Vitamin A Supplement, Pyridoxine Hydrochloride, Menadione Sodium Bisulfite Complex, Manganous Oxide, Copper Sulfate, Ethylenediamine
Dihydriodide ( Source of lodine Vitamin D3 Supplement, Folic Acid, Sodium Selenite), Calcium Carbonate, Brewers Dried Yeast, Malted Barley Flour, Sodium Metabisulfite( Used as a Preservative), AD04.01D9
Number two: The label must properly identify the product.

Number three: A pet food label must including a net quantity statement. This tells you how mucg product is in the container.

Number four: The label must include the manufacturer's or distributor's name and address.

Both the atstes and FDA can inspect pets food manufacturing facilities to make sure the appropriate regulations for manufacturering and labeling products and being followed.


FDA and pets food packaging requirement

15ml pets syringe

Resources come from FDA news

Which drugs need to prevent children from opening the bottle

 "Child-resistant bottles are also called CRC (Child-Resistant Cap) packaging, which originated in the United States in 1970. The "Poison Prevention Packaging Act" (PPPA) stipulates that products harmful to children must be packaged in child-safe packaging, specifically related to drugs Dietary supplement products include the following categories:


Which drugs need to prevent children from opening the bottle

child proof bottle



1. The following human products intended for oral administration: aspirin; prescription drugs and controlled drugs; products containing more than 1 gram of acetaminophen, products containing 1 gram or more of ibuprofen; containing more than 66 mg of diphenhydramine base Equivalent products; and products containing more than 0.045 mg loperamide;

2. The liquid product contains more than 5% of methyl salicylate;

3. For liquids containing 250 mg or more of elemental iron, the concentration is 0.025% or higher by weight/volume; for non-liquids, the concentration is 0.05% or higher by weight/weight;

4. Products containing more than 5 mg lidocaine or 0.5 mg of dibucaine; e) human products containing 250 mg or more of naproxen or 50 mg of ketoprofen;

5. Fluoride-containing products and ethanol-containing mouthwashes. (See the description above.);

6. Human products containing more than 14 mg of minoxidil;

7. Any dosage form that can be taken orally on over-the-counter medicines (OTC), and any medicine containing active ingredients previously only available through prescription.

8. Products containing imidazoline equal to or greater than 0.08 mg.

The above is the US Poison Prevention Packaging Act" for drugs and dietary supplement products that must be bottle-proof for children to open. In addition, it also includes containers containing liquid nicotine, chemicals and cosmetics.


Source: US Consumer Product Safety Commission

Which printing method is better for effervescent tube labels

 "The outer packaging of the medicine represents the image of the pharmaceutical company, and the choice of printing method will directly affect the presentation effect of the packaging label. Then, as an effervescent tube for the special packaging of effervescent tablets, which printing method is used for the external label is more effective Okay?


Which printing method is better for effervescent tube labels

effervescent packaging


The label printing methods on the market now include screen printing and flexographic printing. Not only are the processing techniques complicated, the cycle is long, and the timeliness is poor. To realize the printing of anti-counterfeiting marks such as digital codes and bar codes, it needs to be printed multiple times. With the improvement of customers' requirements for printing quality, an emerging thermal transfer printing method has become a common choice for effervescent tube labels.

Thermal transfer is divided into two parts: transfer film printing and transfer processing. The transfer film printing adopts dot printing, and the pattern is printed on the surface of the film in advance. The printed pattern has rich layers, bright colors, ever-changing, small color difference, and good reproducibility. Can achieve the effect required by the designer, and is suitable for mass production. The transfer process transfers the exquisite patterns on the transfer film to the surface of the product through a heat transfer machine (heating and pressure). After the forming, the ink layer and the product surface are integrated into one, which is vivid and beautiful, greatly improving the quality of the product.

The function of the effervescent tube label is to highlight the characteristics of the product, improve the visual effect of the product, and enhance the anti-counterfeiting performance of the product. Based on the various printing methods currently on the market, thermal transfer can make the finished label display better, and it has become a common choice in the market. "

2021年4月27日星期二

Application of High Density Polyethylene Bottle in Medicine Packaging

With the continuous improvement of various production processes, HDPE raw materials are processed into various forms of high-density polyethylene bottles and used in various industries. Among many applications, pharmaceutical packaging is a relatively special field.


Application of High Density Polyethylene Bottle in Medicine Packaging

60ml HDPE pill bottle with crc



High-density polyethylene is non-toxic, odorless, feels like wax, has excellent low temperature performance, can be used in an environment of -70-100 ℃, is resistant to most acids and alkalis, has good flexibility, and is light and not fragile. . Pharmaceutical packaging is generally divided into two categories: solid and liquid. High-density polyethylene bottles can be used as packaging for solid medicines and liquid medicines. Some liquid medicines are easy to decompose when exposed to light, and will be made into brown bottles by adding color masterbatch to the raw materials to better protect the medicines. Solid medicines are easily deteriorated by moisture, so high-density polyethylene bottles used for solid medicine packaging will add a desiccant to the bottle to maintain the dryness of the environment in the bottle and protect the stability of the medicine.

HDPE pills bottle plays an important role in the safety and effectiveness of drugs. For high-density polyethylene bottles for solid and liquid pharmaceutical packaging, the industry has also formulated corresponding quality standards to determine the appearance, dissolution, drop resistance, and abnormality of the bottles. Toxicity and other indicators and testing methods have been specified in detail to ensure that the packaging quality meets the standard requirements.

High-density polyethylene bottles are currently one of the common packaging in the pharmaceutical industry. In addition, polyester bottles, polypropylene bottles and other polymer material packaging also have a certain range of applications in the field of pharmaceutical packaging. Whether there will be more innovative packaging in the future, we will wait and see.

2021年4月24日星期六

Which printing method is better for effervescent tube labels

The outer packaging of the medicine represents the image of the pharmaceutical company, and the choice of printing method will directly affect the presentation effect of the packaging label. Then, as an effervescent tube for the special packaging of effervescent tablets, which printing method is used for the external label is more effective Okay?


Which printing method is better for effervescent tube labels

effervescent packaging



The label printing methods on the market now include screen printing and flexographic printing. Not only are the processing techniques complicated, the cycle is long, and the timeliness is poor. To realize the printing of anti-counterfeiting marks such as digital codes and bar codes, it needs to be printed multiple times. With the improvement of customers' requirements for printing quality, an emerging thermal transfer printing method has become a common choice for effervescent tube labels.

Thermal transfer is divided into two parts: transfer film printing and transfer processing. The transfer film printing adopts dot printing, and the pattern is printed on the surface of the film in advance. The printed pattern has rich layers, bright colors, ever-changing, small color difference, and good reproducibility. Can achieve the effect required by the designer, and is suitable for mass production. The transfer process transfers the exquisite patterns on the transfer film to the surface of the product through a heat transfer machine (heating and pressure). After the forming, the ink layer and the product surface are integrated into one, which is vivid and beautiful, greatly improving the quality of the product.

The function of the effervescent tube label is to highlight the characteristics of the product, improve the visual effect of the product, and enhance the anti-counterfeiting performance of the product. Based on the various printing methods currently on the market, thermal transfer can make the finished label display better, and it has become a common choice in the market. "

2021年4月21日星期三

The importance of eye drop bottle tightness test

 Eye drops are one of the commonly used pharmaceutical dosage forms for eye diseases. For many eye diseases, eye drops have a direct and rapid therapeutic effect. Because it acts directly on the eyes, eye drops have very strict requirements on the transparency, air tightness, and pressure resistance of the pharmaceutical packaging. Among them, the tightness test is an important test index for the eye drop bottle.


The importance of eye drop bottle tightness test

5ml eye dropper bottle


Tightness refers to the feature of packaging to prevent other substances from entering or the contents from escaping. In the production process of the eye drop bottle, due to the many production links, leaks, press-throughs, or cracks and pores in the material itself may occur, resulting in small holes or weak points of strength between the inside and the outside. If the sealing performance is not up to standard, external water vapor will enter the package and contact the medicine, and the medicine may be contaminated, invalid or deteriorated, which will endanger the health of the patient. Therefore, to ensure the efficacy of the drug within the validity period, a package with good sealing properties must be provided, and the sealing performance test has become one of the basic test items for many drug packages.

Eye drop bottles are generally made of plastic material that is easy to squeeze, and the common one is low-density polyethylene (LDPE). In the YBB20072012 "Low Density Polyethylene Medical Eye Drop Bottles" standard, specific requirements are made for the sealing test method:

(1) Take several test bottles. Under the condition of a torque of 55-80N·cm, both the mouth and the cap should match properly, and the teeth should not be slippery.

(2) Take several test bottles, open the bottles first, and then tighten the caps (the test bottles use a force measuring wrench to tighten the bottles and caps, the torque is 55-80N·cm), and place them in a container with a suction device Afterwards, add a baffle, immerse in water, vacuum to a vacuum of 20kPa, and maintain for 2 minutes. There should be no water or bubbling in the bottle.

There may be slight differences in national standards for the test methods for the tightness of eye drop bottles, but the purpose is to ensure the safety of the drugs and bring better treatment effects for patients. For the tightness test, the manufacturer of the drug packaging Pharmaceutical companies should pay enough attention.

2021年4月20日星期二

Paste syringe manufacturers usher in development opportunities

 With the development of social economy and the improvement of people's living and material conditions, keeping pets has gradually become a trend. And from this, various sub-fields about pet economy are extended, such as pet food, pet medical treatment, pet grooming, etc. As a common veterinary packaging for pet nutrition cream, the paste syringe will also usher in development opportunities under the drive of the industry environment.

Paste syringe manufacturers usher in development opportunities

syringe for pets feeding


At present, the world pet market is growing at an alarming rate, and the number and expenditure of pets in many countries are higher than ever before. In the past 8 years, the global pet market has maintained a year-on-year growth rate of about 5%. The United States, as the world's largest and most mature pet consumer market, has the highest pet industry. As of 2017, the global pet product market has reached US$127.5 billion, a year-on-year increase of 13.3%. From 2012 to 2017, the global pet product market grew from 91.5 billion US dollars to 127.5 billion US dollars, with a compound annual growth rate of 6.86%, and the growth rate continued to be stable.

Affected by the new crown pneumonia epidemic, the status of pets has become more prominent, and global pet consumption will usher in explosive growth in 2020. On the whole, under the influence of factors such as population aging, single economy, capital promotion, etc., the global pet market is a blue ocean, and with it comes the era of great prosperity of the entire pet economy.

Pet nutrition cream is one of the subdivided products in the pet food field. It has a significant effect on weak, elderly dogs and cats, dogs and cats after surgery, physical recovery after surgery, and pets who need to improve immunity. Pet owners are also willing to spend a certain cost. To ensure the healthy growth of pets, and the popularity of pet nutrition cream also brings certain development opportunities to syringe manufacturers.

The pet nutrition cream in the form of a perfusion device is convenient to use, reduces residues, can effectively realize the scientific feeding of pets, and is more conducive to the healthy growth of pets. Consumers will also consider the convenience of use when purchasing pet nutrition cream. Therefore, packaging manufacturers who master the production technology of the infusion device will also usher in a wave of dividends.

Eye drop bottle purchase attention

 Eye drops are commonly used drugs in ophthalmology. A bottle of high-quality eye drops requires a high-quality eye drop bottle to protect it. Pharmaceutical companies can consider the following aspects when purchasing eye drop bottles.


Eye drop bottle purchase attention

eye dropper bottle



1. No matter what raw material you choose, the eye drop bottle must first meet the requirements of non-toxicity and no peculiar smell. The low-density polyethylene (LDPE), polyester (PET) and other materials we see daily can be used as eye drop bottles Based on the raw materials of the drug, the appropriate materials can be selected according to the properties of the drug to better meet its demand for packaging.

2. The airtightness and water vapor permeability of the bottle body and cap. Tightness and water vapor permeability are two important technical indicators of plastic bottles. They have a vital impact on the stability of the packaged product. Pharmaceutical companies need to pay attention to these two indicators when purchasing eye drop bottles.

3. Product quality standards for eye drops. The product quality can be analyzed and judged from the manufacturer's product quality standards, which is convenient for pharmaceutical companies to make correct judgments.

4. Quality assurance system. Auditing suppliers has become an essential part of purchasing eye drop bottles. Through the audit, a comprehensive and correct assessment of the manufacturer's software and hardware facilities, technical equipment, and comprehensive quality level can be made. High-quality manufacturers are more secure in terms of product quality, delivery cycle, and later service.

Eye drops are essential medicines to protect eye health. Pay attention to the importance of eye drops bottles. Choosing high-quality pharmaceutical packaging is a necessary condition to ensure eye health.

2021年4月18日星期日

Effervescent Tablet Tube Test Specification

 The concept of the inspection result exceeding standard management was introduced for the first time, which means that the test result is beyond the legal standard and the enterprise internal control standard. Excessive inspection results do not necessarily mean that the sample inspection is not qualified. How can the effervescent tablet tube manufacturer be implemented?


Effervescent Tablet Tube Test Specification

effervescent packaging



First, the operating procedures for the establishment of inspection results exceeding the limits of the investigation within the company. Laboratory investigation was carried out according to the regulations to confirm whether it was laboratory bias. If it is not the laboratory deviation, the R & D, technology and production personnel should be organized to investigate the production process. It can also be interpreted as two categories: laboratory bias and non laboratory bias.


Effervescent Tablet Tube Test Specification

133*29mm vitamin tablet tube



The laboratory deviation shall investigate any deviation of the test results caused by the factors related to the inspection process,A laboratory survey should be carried out by the professional personnel. The non laboratory deviation refers to the deviation of the test results caused by any other factors except the deviation of the laboratory. The above deviation analysis also standardizes the concrete implementation of the inspection results exceeding the standard for effervescent tablet tube factory. 

Horse paste syringe appearance

 Our factory is a professional horse paste dispensing syringe manufacturer,we have our dial a dose syringe standard,and I will introduce the technical requirements from two aspects,one is sensory requirements,the other one is physical and chemical indicators.


Horse paste syringe appearance

veterinary syringe

I will introduce the appearance requirement of paste syringe.

1.Appearance,in natural light bright place,the syringe should have uniform colors,the surface should bright and clean,smooth,don't have obvious chromatic aberration.

2.The barrel of syringe is not crooked,the syringe don't have rags,deformation,cracks,sand hole,oil contamination,bubble;

3.The inside wall of barrel should be smoothness,don't have crinkle.

4.The syringe tip should be smooth

5.The syringe don't have defective printing which can influence of using


2021年4月16日星期五

equine oral paste administration way in syringe

Horse oral paste in syringe is a common veterinary packaging for horse medicine at home and abroad. It is mainly used in some nutritional creams, anthelmintics and other medicines. The horse is larger in size, and the medicines in this type of packaging are more convenient for administration. So how to administer horse oral paste in syringe?


equine oral paste administration way in syringe

veterinary syringe


The paste syringe is composed of a tube sleeve, a push rod, a piston, a positioning ring, and a protective cap. It has the characteristics of convenient administration, no residue, and reduced pollution. Oral paste medicines for horses are generally based on body weight to determine the dosage. First, before starting the administration, the weight of the animal should be grasped as accurately as possible, the actual dosage should be calculated, and the positioning ring should be set on the scale of the corresponding dosage. , To ensure the accuracy of medication. Remove the protective cap of the perfusion device, insert the tip of the needle into the mouth of the horse in the interdental area, push the push rod, and apply the paste to the base of the tongue. After the administration, immediately raise the horse’s head for a few seconds to ensure that it has swallowed the medicine. under.

It should be noted that the same veterinary syringe can be applied to two different animals only when the two horses are in the same space and in direct contact, otherwise cross-infection is likely to occur. Oral pastes are generally aimed at horses over 4 weeks old and are not suitable for horses that are too young.

The correct way of administration is the key to ensuring the therapeutic effect. The advantages of the veterinary syringe packaging make the dosage of large animals such as horses and cattle more accurate and the process more convenient. It is a new type of packaging recognized by the market.


Several factors of damp inside the effervescent tube

 Effervescent tablets are a kind of solid beverage, which will disintegrate quickly when exposed to water. Therefore, the moisture-proof performance of the effervescent tube is stricter. If the inside of the package is damp and the tablet disintegrates, it is mostly related to these factors.


Several factors of damp inside the effervescent tube

effervescent tablet tube



Moisture-proof is the basic requirement for the pharmaceutical packaging of medicines, especially for some solid medicines. Once the inside of the packaging gets damp, it will easily lead to deterioration or failure of the medicine. If the patient takes the deteriorated medicine by mistake, it will endanger the health of the body. If the inside of the effervescent tube is damp, first consider whether the tightness of the packaging is qualified. The tightness of the effervescent tube mainly depends on the precision of the mold and the control of each production link. Packaging materials generally have moisture barrier properties, which can block the intrusion of external water molecules. However, if the seal is not tight, it is easy to cause water vapor to penetrate into the packaging and make the medicines damp and deteriorate.

On the other hand, also consider the amount of desiccant. The desiccant inside the effervescent tube is mainly a mixture of silica gel and molecular sieve. The drying performance of the desiccant itself is almost the same. If the packaging is well-sealed, the interior of the effervescent tube is still damp, which may be due to dryness. The dosage of the agent is not enough to completely absorb the moisture of the medicine itself, so you can consider increasing the dosage of the desiccant.

In addition, the moisture inside the effervescent tube is also related to the external storage environment. If the external environment is too humid, it is easy to get moisture inside the package. Therefore, when storing the product, choose a dry and ventilated place as much as possible.

The above is the analysis of several main reasons for the internal dampness of the effervescent tube. High-quality packaging is the basic requirement for drug storage. When purchasing effervescent tubes, pharmaceutical companies should pay attention to the product quality while paying attention to the impact of the external storage environment on the drugs.

Paste syringe manufacturers usher in development opportunities

With the development of social economy and the improvement of people's living and material conditions, keeping pets has gradually become a trend. And from this, various sub-fields about pet economy are extended, such as pet food, pet medical treatment, pet grooming, etc. As a common veterinary packaging for pet nutrition cream, the paste syringe will also usher in development opportunities under the drive of the industry environment.

Paste syringe manufacturers usher in development opportunities

syringe for pets feeding


At present, the world pet market is growing at an alarming rate, and the number and expenditure of pets in many countries are higher than ever before. In the past 8 years, the global pet market has maintained a year-on-year growth rate of about 5%. The United States, as the world's largest and most mature pet consumer market, has the highest pet industry. As of 2017, the global pet product market has reached US$127.5 billion, a year-on-year increase of 13.3%. From 2012 to 2017, the global pet product market grew from 91.5 billion US dollars to 127.5 billion US dollars, with a compound annual growth rate of 6.86%, and the growth rate continued to be stable.

Affected by the new crown pneumonia epidemic, the status of pets has become more prominent, and global pet consumption will usher in explosive growth in 2020. On the whole, under the influence of factors such as population aging, single economy, capital promotion, etc., the global pet market is a blue ocean, and with it comes the era of great prosperity of the entire pet economy.

Pet nutrition cream is one of the subdivided products in the pet food field. It has a significant effect on weak, elderly dogs and cats, dogs and cats after surgery, physical recovery after surgery, and pets who need to improve immunity. Pet owners are also willing to spend a certain cost. To ensure the healthy growth of pets, and the popularity of pet nutrition cream also brings certain development opportunities to syringe manufacturers.

The pet nutrition cream in the form of a perfusion device is convenient to use, reduces residues, can effectively realize the scientific feeding of pets, and is more conducive to the healthy growth of pets. Consumers will also consider the convenience of use when purchasing pet nutrition cream. Therefore, packaging manufacturers who master the production technology of the infusion device will also usher in a wave of dividends.


 

Eye drop bottle purchase attention

 Eye drops are commonly used drugs in ophthalmology. A bottle of high-quality eye drops requires a high-quality eye drop bottle to protect it. Pharmaceutical companies can consider the following aspects when purchasing eye drop bottles.


Eye drop bottle purchase attention

eye dropper bottle



1. No matter what raw material you choose, the eye drop bottle must first meet the requirements of non-toxicity and no peculiar smell. The low-density polyethylene (LDPE), polyester (PET) and other materials we see daily can be used as eye drop bottles Based on the raw materials of the drug, the appropriate materials can be selected according to the properties of the drug to better meet its demand for packaging.

2. The airtightness and water vapor permeability of the bottle body and cap. Tightness and water vapor permeability are two important technical indicators of plastic bottles. They have a vital impact on the stability of the packaged product. Pharmaceutical companies need to pay attention to these two indicators when purchasing eye drop bottles.

3. Product quality standards for eye drops. The product quality can be analyzed and judged from the manufacturer's product quality standards, which is convenient for pharmaceutical companies to make correct judgments.

4. Quality assurance system. Auditing suppliers has become an essential part of purchasing eye drop bottles. Through the audit, a comprehensive and correct assessment of the manufacturer's software and hardware facilities, technical equipment, and comprehensive quality level can be made. High-quality manufacturers are more secure in terms of product quality, delivery cycle, and later service.

Eye drops are essential medicines to protect eye health. Pay attention to the importance of eye drops bottles. Choosing high-quality pharmaceutical packaging is a necessary condition to ensure eye health.

The importance of effervescent tube packaging material selection

 The effervescent tube is a special packaging used to hold vitamin C effervescent tablets. The effervescent tablet contains a disintegrant and is easy to decompose when exposed to moisture. Therefore, the moisture-proof and tightness of the packaging are relatively high, and the choice of effervescent tube packaging material.The overall performance of the packaging is an important consideration for pharmaceutical companies when choosing packaging.


The importance of effervescent tube material selection

effervescent tablet tube



At present, the materials of pharmaceutical packaging generally use polyethylene, polypropylene, polyester and other materials, which have the characteristics of light texture, resistance to most acid and alkali corrosion, easy processing and molding, good sealing performance, and strong impact resistance, which basically meet the requirements of most pharmaceutical packaging. Demand. Polyester material is mostly used for liquid medicine or medicine packaging that requires transparency. The material of the effervescent tube packaging is mainly polypropylene and polyethylene, and the bottle body is made of polypropylene, which can achieve good impact resistance. To protect the safety of medicines, the bottle body of this material has good gloss, which is convenient for printing and labeling.

The cap of the effervescent tube is made of polyethylene. This material has good flexibility and heat-seal performance. Its transparency varies with molecular weight. It can achieve a good sealing effect and prevent the intrusion of external water vapor. Prevent the effervescent tablet from being decomposed by moisture.

Choosing suitable packaging materials for drugs is the basic requirement to meet their storage needs and ensure the efficacy of the drug during the validity period. The use of different materials for the body and cap of the effervescent tube is to better meet the requirements of the effervescent tablet for sealing. Pharmaceutical companies should fully realize the importance of materials for drug performance when choosing drug packaging, and choose the best.

2021年4月13日星期二

Application of double-neck bottle in disinfectant packaging

 Disinfectant is almost a necessary cleaning product for every family, and it is widely used in agriculture, medical treatment, animal husbandry and other fields. Disinfectants need to be diluted before they can be used. The veterinary packaging is mostly plastic bottles. In order to facilitate the control of the dilution ratio in use, a two neck bottle with a quantitative function has gradually become the first choice for disinfectant packaging.


Application of double-neck bottle in disinfectant packaging

twin neck bottle


Most disinfectants are corrosive at high concentrations and can damage the environment, objects, and animal mucous membranes. Especially for animal mucosa, the volatilization of high-concentration disinfectants will cause mucosal damage, resulting in mucosal congestion, bleeding, and local ulceration. Therefore, the dilution concentration of the disinfectant is related to the disinfection effect. The higher the concentration, the better, the appropriate dilution ratio can minimize the adverse effects on the human body and the environment.

In view of the importance of the dilution ratio of the disinfectant, it is generally necessary to control the specific concentration with the help of a measuring cup. In order to be convenient to use, packaging manufacturers have developed a two-neck bottle packaging that combines storage and quantitative functions in combination with the actual needs of the market. This kind of packaging adopts two bottle mouth designs, namely the bottle mouth of the quantitative bottle with marking and the bottle mouth for storing disinfectant. When using, open the cap of the quantitative bottle and gently squeeze the bottle body to make the appropriate amount of disinfectant enter the quantitative bottle. Pour the amount of disinfectant into the dilution container according to the usage amount. This method of use reduces the intermediate steps of pouring the disinfectant into the measuring cup, and can reduce waste while being convenient to use.

At present, two-neck bottles have been widely used in the packaging of animal nutrition solutions, disinfectants, herbicides, pesticides, etc., and consumers are more willing to choose such convenient packaging when purchasing drugs.

Several factors of damp inside the effervescent tube

 Effervescent tablets are a kind of solid beverage, which will disintegrate quickly when exposed to water. Therefore, the moisture-proof performance of the effervescent tube is stricter. If the inside of the package is damp and the tablet disintegrates, it is mostly related to these factors.


Several factors of damp inside the effervescent tube

effervescent tablet tube



Moisture-proof is the basic requirement for the pharmaceutical packaging of medicines, especially for some solid medicines. Once the inside of the packaging gets damp, it will easily lead to deterioration or failure of the medicine. If the patient takes the deteriorated medicine by mistake, it will endanger the health of the body. If the inside of the effervescent tube is damp, first consider whether the tightness of the packaging is qualified. The tightness of the effervescent tube mainly depends on the precision of the mold and the control of each production link. Packaging materials generally have moisture barrier properties, which can block the intrusion of external water molecules. However, if the seal is not tight, it is easy to cause water vapor to penetrate into the packaging and make the medicines damp and deteriorate.

On the other hand, also consider the amount of desiccant. The desiccant inside the effervescent tube is mainly a mixture of silica gel and molecular sieve. The drying performance of the desiccant itself is almost the same. If the packaging is well-sealed, the interior of the effervescent tube is still damp, which may be due to dryness. The dosage of the agent is not enough to completely absorb the moisture of the medicine itself, so you can consider increasing the dosage of the desiccant.

In addition, the moisture inside the effervescent tube is also related to the external storage environment. If the external environment is too humid, it is easy to get moisture inside the package. Therefore, when storing the product, choose a dry and ventilated place as much as possible.

The above is the analysis of several main reasons for the internal dampness of the effervescent tube. High-quality packaging is the basic requirement for drug storage. When purchasing effervescent tubes, pharmaceutical companies should pay attention to the product quality while paying attention to the impact of the external storage environment on the drugs.

The mouth design of HDPE pill bottles should pay attention to these details

High-density polyethylene bottles are more common in pharmaceutical packaging, such as tablets, capsules, oral liquids and other drugs will choose this packaging. In the bottle design, pharmaceutical companies generally pay attention to whether the appearance is beautiful, whether it can meet the characteristics of the drug and storage needs. In fact, the design of the mouth of the high-density polyethylene bottle is also very important.

The mouth design of HDPE pill bottles should pay attention to these details

HDPE bottle for pharmaceutical


The appearance of high-density polyethylene bottles is the first impression of consumers, the epitome of brand image, and the primary factor that pharmaceutical companies pay attention to. There are also some more strict manufacturers who will evaluate the grip of the bottle and the convenience of use. In fact, the design of the bottle mouth is also related to many problems.

The first is the size of the caliber of the high-density polyethylene bottle, which is directly related to the convenience of consumers. For example, the mouth of the oral liquid bottle is too large, it is easy to spill when the liquid is poured, and the mouth is too small and not It is conducive to filling, so a reasonable bottle caliber is very important.

On the other hand is the standard issue of caliber. The high-density polyethylene bottle has a uniform caliber, which is conducive to the matching of caps and is suitable for the production of industrialized manufacturers. In addition, it also involves the sealing problem of the bottle mouth. A reasonable bottle mouth design is conducive to the attachment of the sealing film and can make the sealing of the package more reliable.

In summary, not only high-density polyethylene bottles, pharmaceutical packaging material manufacturers should also pay more attention to the design of the bottle mouth when producing other medical plastic bottles to improve the overall quality of the product.


2021年4月12日星期一

Application of twin-neck bottle in veterinary insect repellent drugs

 Parasitic diseases are common diseases in the livestock breeding industry, and regular deworming of livestock is also an important task in the daily management of farms. At present, the anthelmintic drugs on the market are mainly powder and liquid preparations. For the convenience of use, an anthelmintic drug package with a two-neck bottle design has been universally recognized by the market.


Application of twin-neck bottle in veterinary insect repellent drugs

1000ml dispensing bottle with twin neck


Veterinary anthelmintics are mainly used for the prevention and treatment of nematode diseases, mites and parasitic insect diseases in sheep and pigs. From the perspective of the route of administration, veterinary anthelmintics are mostly used by injection, oral administration, painting, etc., depending on the dosage form. , The method of administration is also different. The emergence of two-neck bottle packaging has made the route of administration more diversified, and has also given farmers more choices.

There is a water barrier inside the bottle body of the two-neck bottle. The water barrier divides the bottle body into an upper water tank and a lower water tank. The upper water tank is marked with a scale and can be used as a quantitative bottle. The lower water tank is a space for storing medicines. When in use, open the cap of the measuring bottle and gently squeeze the bottle body to make the appropriate amount of medicine enter the quantitative bottle. The mouth of the measuring bottle is on the top and the mouth of the medicine bottle is on the bottom. The back midline is poured onto the back of the livestock. The liquid medicine can penetrate into the body through the back of the livestock to achieve the effect of deworming. This kind of packaging combines quantitative and storage functions into one, making the way of administration more convenient.

The innovation of science and technology has caused continuous changes in all walks of life, and the emergence of two-neck bottles is the product of this change. Veterinary drug companies should not only focus on product quality in the choice of veterinary packaging, but also need to think more about the convenience of customers.